Gene: ZNF382
Official Full Name: zinc finger protein 382provided by HGNC
Gene Summary: This gene encodes a KRAB domain zinc finger transcription factor (KZNF). KZNFs play critical roles in the regulation of many cellular processes including differentiation, proliferation and apoptosis. The encoded protein inhibits activating protein 1 (AP-1) and nuclear factor kappa-B (NF-kB) signaling and may function as a tumor suppressor in multiple carcinomas. This gene is found in a cluster with other zinc finger protein genes on the long arm of chromosome 19, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24493 | ZNF382 Knockout cell line (HEK293) | Human | ZNF382 | 1:3~1:6 | Negative | Online Inquiry |
ZNF382 Gene Knockout Cell Lines are specialized cellular models engineered to lack the ZNF382 gene, which plays a significant role in various biological processes, including gene regulation and cellular differentiation. These knockout cell lines are developed using sophisticated genetic editing technologies, such as CRISPR/Cas9, allowing for precise alterations to the genome. By inactivating the ZNF382 gene, researchers can effectively study the resultant phenotypes, elucidating the gene's functions and its impact on cellular behavior and pathways.
The primary function of ZNF382 gene knockout cell lines is to serve as a powerful tool for functional genomics research, enabling detailed investigation into the biological roles of ZNF382. The absence of this gene can lead to altered signaling pathways, changes in cell proliferation, and variations in gene expression profiles, making these models invaluable in understanding the gene’s contributions to diseases, such as cancers or other disorders. Furthermore, they can be utilized to screen for therapeutic compounds that may target the pathways influenced by ZNF382.
Scientifically, these cell lines hold significant importance in both research and clinical settings. They facilitate the study of gene functionality in a controlled environment and can support therapeutic development by providing insights into potential biomarkers or drug targets. Moreover, ZNF382 knockout cells can inform researchers about the underlying mechanisms of drug resistance or sensitivity.
Compared to conventional cell lines, ZNF382 gene knockout cell lines offer unparalleled specificity and relevance to studies involving ZNF382-associated mechanisms. They eliminate the confounding effects of the gene, allowing for clearer insights and interpretations. These models are particularly advantageous for researchers focusing on gene therapy, synthetic biology, and targeted therapeutic strategies.
For researchers and clinicians, leveraging ZNF382 gene knockout cell lines can accelerate discoveries, enhance experimental outcomes, and promote innovations in treatment approaches. At [Company Name], we pride ourselves on our expertise in genetic engineering and our commitment to delivering high-quality, reliable biological research tools. Our ZNF382 gene knockout cell lines exemplify our dedication to advancing research and improving therapeutic strategies through precision biology.
Please note that all services are for research use only. Not intended for any clinical use.
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