Gene: ZNF354C
Official Full Name: zinc finger protein 354Cprovided by HGNC
Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of sprouting angiogenesis. Located in cytoplasm; nuclear membrane; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26738 | ZNF354C Knockout cell line (A549) | Human | ZNF354C | 1:3~1:4 | Negative | Online Inquiry |
ZNF354C Gene Knockout Cell Lines represent a revolutionary tool in the field of molecular biology, specifically designed to facilitate the study of the ZNF354C gene's role in various cellular processes and its implications in disease mechanisms. These cell lines have been genetically engineered to lack the expression of the ZNF354C gene, enabling researchers to investigate the functional consequences of ZNF354C deletion on gene expression, cell signaling pathways, and overall cellular behavior.
The core function of ZNF354C Gene Knockout Cell Lines lies in their ability to provide a precise model for studying gene function. By utilizing CRISPR/Cas9 gene editing technology, these knockout cell lines exhibit complete gene disruption, allowing for the assessment of the effects on cellular phenotypes, such as proliferation, differentiation, and response to external stimuli. Researchers can apply these cell lines in various experimental setups to elucidate the pathway interactions and regulatory networks involving ZNF354C, fostering a deeper understanding of its biological significance.
The scientific importance of ZNF354C Gene Knockout Cell Lines is underscored by their potential applications in both research and clinical settings. In a research context, they can be used to model diseases, such as cancer, where ZNF354C is implicated. Additionally, these cell lines can support drug discovery and development initiatives by enabling the screening of therapeutic compounds targeting pathways influenced by ZNF354C.
Compared to traditional methods of gene silencing, such as RNA interference, ZNF354C Gene Knockout Cell Lines offer several significant advantages. The knockout approach ensures permanent gene disruption, allowing for more robust and reproducible experimental results. Furthermore, these cell lines are extremely versatile and can be adapted for a broad range of assays, including gene expression profiling, functional assays, and high-throughput screening.
For researchers and clinicians alike, the inherent value of ZNF354C Gene Knockout Cell Lines lies in their capacity to enhance the understanding of gene function and its implications for health and disease. These tools empower investigators to make significant strides in uncovering the biological roles of ZNF354C while paving the way for novel therapeutic strategies.
Our company, with its strong emphasis on cutting-edge genetic engineering techniques and a commitment to advancing biomedical research, is proud to offer ZNF354C Gene Knockout Cell Lines as part of our extensive portfolio of innovative tools for life science research.
Please note that all services are for research use only. Not intended for any clinical use.
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