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ZNF329 Knockout Cell Lines

Gene: ZNF329

Official Full Name: zinc finger protein 329provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12297 ZNF329 Knockout cell line (HeLa) Human ZNF329 1:3~1:6 Negative Online Inquiry
KO12298 ZNF329 Knockout cell line (HCT 116) Human ZNF329 1:2~1:4 Negative Online Inquiry
KO12299 ZNF329 Knockout cell line (HEK293) Human ZNF329 1:3~1:6 Negative Online Inquiry
KO12300 ZNF329 Knockout cell line (A549) Human ZNF329 1:3~1:4 Negative Online Inquiry

Background

ZNF329 gene knockout cell lines are genetically modified cellular models designed to facilitate the functional exploration of the ZNF329 gene, which encodes a zinc finger transcription factor implicated in various biological processes, including cell differentiation and proliferation. These cell lines are engineered through precise gene editing techniques, such as CRISPR-Cas9, to create a complete loss-of-function mutation of ZNF329, thereby providing a vital tool in the study of its role in gene regulation and associated pathways.

The primary function of these knockout cell lines is to serve as a model to analyze the phenotypic consequences resulting from the absence of ZNF329 expression. The mechanism involves disrupting the transcriptional regulatory functions mediated by ZNF329, allowing researchers to observe alterations in gene expression profiles, cellular behavior, and downstream biological effects. This capability is particularly valuable in research contexts focusing on developmental biology, cancer research, and therapeutic targets, where understanding the role of transcription factors is crucial.

In scientific research and clinical applications, ZNF329 gene knockout cell lines offer significant advantages over traditional methods, such as using wild-type cell lines. They allow for direct observation of gene function in real time, streamline the validation of genetic interactions, and enable targeted treatments geared towards specific pathways influenced by the ZNF329 gene. Furthermore, these cell lines can be employed in drug screening assays, providing insights into novel therapeutic approaches for diseases where ZNF329 plays a critical role.

For researchers and clinicians, the immediate benefit of utilizing ZNF329 knockout cell lines is the potential to uncover mechanistic insights that lead to the development of innovative treatments. The ability to systematically manipulate and analyze gene function supports hypothesis-driven investigations, equipping scientists with the tools necessary to make breakthroughs.

Our commitment at [Your Company Name] to advanced genetic tools and innovative biological products positions us as a leader in the field. With expertise in gene editing technologies and a diverse portfolio of genetically engineered cell lines, we aim to empower researchers and clinicians seeking to further understand the complexities of gene function and disease mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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