Gene: ZNF263
Official Full Name: zinc finger protein 263provided by HGNC
Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32261 | ZNF263 Knockout cell line (HeLa) | Human | ZNF263 | 1:3~1:6 | Negative | Online Inquiry |
KO32262 | ZNF263 Knockout cell line (HCT 116) | Human | ZNF263 | 1:2~1:4 | Negative | Online Inquiry |
KO32263 | ZNF263 Knockout cell line (HEK293) | Human | ZNF263 | 1:3~1:6 | Negative | Online Inquiry |
KO32264 | ZNF263 Knockout cell line (A549) | Human | ZNF263 | 1:3~1:4 | Negative | Online Inquiry |
ZNF263 Gene Knockout Cell Lines represent a cutting-edge biological tool employed in molecular biology and genetic research. These cell lines have been genetically engineered to lack the ZNF263 gene, a member of the zinc finger protein family known for its role in transcriptional regulation and cellular signaling pathways. By utilizing CRISPR-Cas9 technology, these knockout cell lines facilitate in-depth analysis of ZNF263 function and its implications in various cellular processes, including cell proliferation, differentiation, and response to stressors.
Key functions of ZNF263 include its involvement in gene silencing and chromatin remodeling, making it essential for understanding intricate regulatory networks within the cell. In research and clinical settings, ZNF263 gene knockout cell lines are invaluable for elucidating the gene's role in disease states, particularly in cancer biology, where aberrations in transcriptional regulation are common. Such insights can pave the way for identifying novel therapeutic targets and biomarkers.
One of the most significant advantages of ZNF263 knockout cell lines is the specificity of gene disruption, which allows for clearer interpretations of experimental results compared to traditional knockdown methods that may produce off-target effects. Additionally, the high efficiency of the CRISPR-Cas9 system ensures a more consistent and reproducible genetic modification.
Researchers and clinicians looking to investigate the molecular functions of the ZNF263 gene will find these knockout cell lines essential for their studies. The ability to derive insights from these engineered systems not only enhances our understanding of gene contributions to health and disease but also supports the development of targeted interventions.
With a commitment to advancing genomics and gene editing technologies, our company specializes in providing high-quality genetic products, including the ZNF263 Gene Knockout Cell Lines, designed to empower researchers in their quest to unlock the complexities of gene function.
Please note that all services are for research use only. Not intended for any clinical use.
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