Gene: ZNF215
Official Full Name: zinc finger protein 215provided by HGNC
Gene Summary: This gene is imprinted in a tissue-specific manner with preferential expression in the testis, and encodes a zinc finger protein that belongs to a family of zinc finger transcription factors. The encoded protein contains an N-terminal SRE-ZBP, Ctfin51, AW-1, and Number 18 (SCAN) domain, a kruppel-associated box A (KRABA) domain, and four C-terminal zinc finger domains. This gene is located within one of three regions on chromosome 11p15 associated with Beckwith-Wiedemann syndrome, called Beckwith-Wiedemann syndrome chromosome region-2 (BWSCR2), and is thought to play a role in the etiology of this disease. [provided by RefSeq, Aug 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34500 | ZNF215 Knockout cell line (HCT 116) | Human | ZNF215 | 1:2~1:4 | Negative | Online Inquiry |
KO34501 | ZNF215 Knockout cell line (HEK293) | Human | ZNF215 | 1:3~1:6 | Negative | Online Inquiry |
KO34502 | ZNF215 Knockout cell line (A549) | Human | ZNF215 | 1:3~1:4 | Negative | Online Inquiry |
ZNF215 Gene Knockout Cell Lines are highly specialized genetically engineered cell lines specifically designed to silence the ZNF215 gene, a member of the zinc finger protein family implicated in various biological processes, including transcriptional regulation and cellular differentiation. The knockout effect is achieved through advanced CRISPR/Cas9 technology, which creates precise double-strand breaks in the target gene, enabling researchers to study the resulting phenotypic changes and functional consequences of ZNF215 absence.
The key function of ZNF215 Gene Knockout Cell Lines is to facilitate in-depth exploration of gene-function relationships and regulatory pathways influenced by the ZNF215 gene. By eliminating this gene, scientists can gain insights into its role in cellular mechanisms and disease states such as cancer, neurological disorders, and metabolic syndromes. The applicability of these cell lines extends to various research settings, such as drug discovery, gene therapy, and molecular biology, where understanding the effects of gene loss is critical for advancing therapeutic strategies.
In comparison to traditional methods of gene silencing, such as RNA interference, ZNF215 Gene Knockout Cell Lines provide a more stable and permanent solution for assessing gene function. This unique selling point ensures that researchers achieve reliable and reproducible results, minimizing off-target effects often associated with transient knockdown approaches.
This product stands out not only for its technical precision but also for its profound implications in identifying potential biomarkers for diseases and developing targeted therapies. Researchers and clinicians utilizing ZNF215 Gene Knockout Cell Lines will find them invaluable tools for unraveling complex genetic interactions and enhancing therapeutic interventions.
With a focus on cutting-edge genetic tools and a commitment to supporting scientific advancement, our company is dedicated to delivering high-quality biological research products that empower researchers and clinicians alike to make groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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