Gene: ZNF205
Official Full Name: zinc finger protein 205provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of hydrogen peroxide biosynthetic process; and positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrion and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34489 | ZNF205 Knockout cell line (HeLa) | Human | ZNF205 | 1:3~1:6 | Negative | Online Inquiry |
KO34490 | ZNF205 Knockout cell line (HCT 116) | Human | ZNF205 | 1:2~1:4 | Negative | Online Inquiry |
KO34491 | ZNF205 Knockout cell line (HEK293) | Human | ZNF205 | 1:3~1:6 | Negative | Online Inquiry |
KO34492 | ZNF205 Knockout cell line (A549) | Human | ZNF205 | 1:3~1:4 | Negative | Online Inquiry |
ZNF205 Gene Knockout Cell Lines are specifically engineered cellular models designed to investigate the biological roles of the ZNF205 gene, which encodes a protein implicated in various cellular processes such as transcription regulation and chromatin remodeling. These knockout cell lines are created through precise genome editing techniques, such as CRISPR-Cas9, enabling researchers to eliminate the expression of the ZNF205 gene and study the resulting phenotypic changes.
The primary function of the ZNF205 Gene Knockout Cell Lines is to facilitate the elucidation of gene function and its involvement in cellular signaling pathways. By creating a controlled environment where the gene of interest is absent, researchers can observe the downstream effects on cellular proliferation, differentiation, and apoptosis, thereby gaining insights into the gene’s contribution to disease states like cancer or developmental disorders.
In terms of scientific importance, these cell lines serve as invaluable tools in both fundamental and applied research. They can be utilized to screen for potential therapeutic targets and to validate drug efficacy in disease models, particularly in conditions where ZNF205 is known to play a role. Furthermore, such models can significantly accelerate translational research by providing crucial preclinical data.
Compared to alternative methods such as transient knockdown approaches or pharmacological inhibitors, ZNF205 Gene Knockout Cell Lines offer a stable and reproducible knockout model that avoids the confounding effects of off-target interference. This specificity enhances the reliability of experimental outcomes, making it easier for researchers to draw clear conclusions from their studies.
For researchers and clinicians focused on molecular biology, genetics, or biomedical research, ZNF205 Gene Knockout Cell Lines are indispensable for advancing our understanding of gene function and its implications in health and disease. The carefully curated knockout models ensure high-quality results that can drive significant advancements in therapeutic strategies.
Our company is committed to providing high-caliber biological products that empower scientific discovery. With a focus on precision and innovation, we strive to support the research community by offering products that not only meet but exceed the expectations in cutting-edge research and therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
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