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ZNF101 Knockout Cell Lines

Gene: ZNF101

Official Full Name: zinc finger protein 101provided by HGNC

Gene Summary: Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform many key functions, the most important of which is regulating transcription (summary by Bellefroid et al., 1993 [PubMed 8467795]). See ZNF91 (MIM 603971) for general information on ZNFs.[supplied by OMIM, Nov 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22094 ZNF101 Knockout cell line (HeLa) Human ZNF101 1:3~1:6 Negative Online Inquiry
KO22095 ZNF101 Knockout cell line (HCT 116) Human ZNF101 1:2~1:4 Negative Online Inquiry
KO22096 ZNF101 Knockout cell line (HEK293) Human ZNF101 1:3~1:6 Negative Online Inquiry
KO22097 ZNF101 Knockout cell line (A549) Human ZNF101 1:3~1:4 Negative Online Inquiry

Background

ZNF101 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZNF101 gene has been systematically disrupted or "knocked out." This process is achieved using advanced gene editing techniques, such as CRISPR-Cas9, enabling researchers to explore the specific biological roles and downstream effects of ZNF101 in various cellular contexts. By eliminating the expression of ZNF101, these cell lines serve as invaluable tools for studying gene function, signaling pathways, and the impact of gene loss on cellular phenotypes.

The functioning of ZNF101 Gene Knockout Cell Lines hinges on the targeted inactivation of the ZNF101 gene, which is known to play a crucial role in transcriptional regulation and has been implicated in various biological processes, including cell differentiation and apoptosis. This knockout allows researchers to discern the physiological contributions of ZNF101, examine compensatory mechanisms in co-regulated pathways, and assess the gene's involvement in disease states such as cancer.

The scientific importance of ZNF101 Gene Knockout Cell Lines extends to both research and clinical applications. They can be utilized in drug discovery, cancer biology, and genetic research, providing insights into gene therapy possibilities and the development of novel therapeutic agents. These cell lines allow for rigorous investigation of gene function, enhancing our understanding of complex genetic interactions and facilitating the identification of potential biomarkers for therapeutic targeting.

Compared to alternative models, such as wild-type or knockdown cell lines, ZNF101 Gene Knockout Cell Lines offer precise and uniform disruption of the target gene, leading to more definitive conclusions regarding gene function. They also mitigate off-target effects often associated with RNA interference, ensuring that observed changes in phenotype are directly related to ZNF101 loss.

For researchers, clinicians, and biopharmaceutical developers, the value of ZNF101 Gene Knockout Cell Lines lies in their ability to provide reliable and reproducible data conducive to advancing our understanding of gene function and disease mechanisms. By integrating ZNF101 cell lines into research workflows, professionals can enhance the precision of their studies and accelerate the translation of findings into clinical solutions.

Our company specializes in the development of high-quality biological products, including ZNF101 Gene Knockout Cell Lines, ensuring that researchers have access to the tools necessary to push the boundaries of innovation in genetic research and therapeutic applications.

Please note that all services are for research use only. Not intended for any clinical use.

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