Gene: ZKSCAN4
Official Full Name: zinc finger with KRAB and SCAN domains 4provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12361 | ZKSCAN4 Knockout cell line (HeLa) | Human | ZKSCAN4 | 1:3~1:6 | Negative | Online Inquiry |
KO12362 | ZKSCAN4 Knockout cell line (HCT 116) | Human | ZKSCAN4 | 1:2~1:4 | Negative | Online Inquiry |
KO12363 | ZKSCAN4 Knockout cell line (HEK293) | Human | ZKSCAN4 | 1:3~1:6 | Negative | Online Inquiry |
KO12364 | ZKSCAN4 Knockout cell line (A549) | Human | ZKSCAN4 | 1:3~1:4 | Negative | Online Inquiry |
ZKSCAN4 Gene Knockout Cell Lines are engineered cellular models designed for the precise investigation of the ZKSCAN4 gene’s role in various biological processes. This product is created using advanced CRISPR-Cas9 gene editing technology, which allows for the targeted disruption of the ZKSCAN4 gene, leading to the development of knockout lines that are invaluable for functional genomics studies. These cell lines enable researchers to explore the gene's implications in cellular regulation, developmental biology, and potentially its contributions to various diseases, including cancer.
The key mechanism behind the functionality of ZKSCAN4 Gene Knockout Cell Lines lies in the CRISPR-Cas9 system, which employs a guide RNA to direct the Cas9 nuclease to the specific genomic locus of the ZKSCAN4 gene, resulting in a double-strand break that is repaired by an error-prone process. This process often leads to insertions or deletions, effectively knocking out the gene's expression. This allows for comprehensive analysis of gene function, signaling pathways, and downstream effects in cellular behavior, enabling targeted screening and therapeutic development.
Scientifically, the importance of ZKSCAN4 Gene Knockout Cell Lines cannot be overstated. They serve as powerful tools in research environments where elucidating the biological pathways associated with ZKSCAN4 is critical. Applications include drug discovery, functional assays, and the study of gene-environment interactions in model systems, enhancing our understanding of gene function in health and disease.
Compared to conventional gene silencing methods such as RNA interference, ZKSCAN4 Gene Knockout Cell Lines provide a permanent knockout solution, leading to more robust and reproducible gene function studies. The stable nature of these cell lines ensures that experimental results are consistent, making them highly advantageous for researchers seeking definitive insights into gene mechanics.
For researchers and clinicians, investing in ZKSCAN4 Gene Knockout Cell Lines not only facilitates breakthrough discoveries but also underpins innovative approaches in therapeutic development. With a commitment to scientific excellence, our company offers these cell lines backed by extensive validation and support, ensuring customers access cutting-edge resources to advance their research.
Please note that all services are for research use only. Not intended for any clinical use.
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