Gene: ZFAND2A
Official Full Name: zinc finger AN1-type containing 2Aprovided by HGNC
Gene Summary: Predicted to enable zinc ion binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein targeting to ER. Predicted to act upstream of or within cellular response to arsenic-containing substance and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome complex. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23703 | ZFAND2A Knockout cell line (HeLa) | Human | ZFAND2A | 1:3~1:6 | Negative | Online Inquiry |
KO23704 | ZFAND2A Knockout cell line (HCT 116) | Human | ZFAND2A | 1:2~1:4 | Negative | Online Inquiry |
KO23705 | ZFAND2A Knockout cell line (HEK293) | Human | ZFAND2A | 1:3~1:6 | Negative | Online Inquiry |
KO23706 | ZFAND2A Knockout cell line (A549) | Human | ZFAND2A | 1:3~1:4 | Negative | Online Inquiry |
ZFAND2A Gene Knockout Cell Lines represent an innovative tool for molecular biology research that provides a unique platform for studying gene function and regulation. These cell lines are engineered to have a targeted knockout of the ZFAND2A gene, which encodes a protein implicated in various cellular processes, including stress response, cell proliferation, and apoptosis. By eliminating this gene, researchers can dissect its role in various biological pathways and assess the downstream effects on cellular behavior.
The primary function of the ZFAND2A gene knockout cell lines is to facilitate the elucidation of the gene's contributions to physiological and pathological conditions. Researchers can utilize these cell lines to perform loss-of-function studies, observing cellular responses to stressors or the therapeutic effects of potential treatments. The mechanism behind this knockout involves CRISPR-Cas9 technology, which allows for precise genomic edits, enabling researchers to generate stable, reproducible models for diverse studies.
The scientific importance of these cell lines lies in their applicability in both fundamental research and clinical investigations. They can be instrumental in unraveling the implications of ZFAND2A in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Additionally, by using these cell lines, scientists can explore potential targets for drug discovery and therapeutic interventions.
Compared to traditional knockout models, ZFAND2A Gene Knockout Cell Lines offer enhanced specificity and reduced off-target effects, which leads to more reliable data. Their robustness and reproducibility make them ideal for high-throughput screening applications and critical assessments of genetic functions in various contexts.
For researchers and clinicians, the value of ZFAND2A Gene Knockout Cell Lines is clear: they provide a novel approach to understanding the complexities of gene regulation in health and disease. By integrating these cell lines into their studies, professionals can gain insights that drive advancements in medical research and therapeutic development.
Our company is dedicated to empowering scientific exploration and innovation. With a team of experts in gene editing and cellular biology, we ensure that our products meet the highest standards of quality and functionality, enabling researchers to unlock new discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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