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ZDHHC20 Knockout Cell Lines

Gene: ZDHHC20

Official Full Name: zDHHC palmitoyltransferase 20provided by HGNC

Gene Summary: Enables protein-cysteine S-palmitoyltransferase activity and zinc ion binding activity. Involved in peptidyl-L-cysteine S-palmitoylation and positive regulation by host of viral process. Located in Golgi membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00557 ZDHHC20 gRNA4-gRNA5 KO plasmid ZDHHC20 $850
KO01296 ATG7 Knockout cell line (VERO C1008 (E6)) Green monkey ZDHHC20 1:2~1:4 Negative Online Inquiry
KO21202 ZDHHC20 Knockout cell line (HeLa) Human ZDHHC20 1:3~1:6 Negative Online Inquiry
KO21203 ZDHHC20 Knockout cell line (HCT 116) Human ZDHHC20 1:2~1:4 Negative Online Inquiry
KO21204 ZDHHC20 Knockout cell line (HEK293) Human ZDHHC20 1:3~1:6 Negative Online Inquiry
KO21205 ZDHHC20 Knockout cell line (A549) Human ZDHHC20 1:3~1:4 Negative Online Inquiry

Background

ZDHHC20 Gene Knockout Cell Lines are genetically engineered cell models characterized by the complete disruption of the ZDHHC20 gene, which is implicated in various cellular processes including protein acylation. The knockout of this gene enables researchers to study the role of ZDHHC20 in cellular signaling, development, and disease mechanisms more effectively, as the absence of this gene provides a unique platform to investigate its functional impacts without confounding variables.

The key mechanism underlying these cell lines is the use of CRISPR-Cas9 technology, which facilitates precise gene editing to create a targeted knockout. This process allows for the evaluation of the ZDHHC20-dependent pathways in vitro, providing insights into how this gene influences lipid modifications of proteins and overall cell behavior in response to internal and external cues.

Scientifically, ZDHHC20 has been linked to disorders such as neurodegenerative diseases and cancer, positioning these knockout cell lines as valuable tools in both research and clinical settings. By enabling the dissection of the biological roles of ZDHHC20, these models support the exploration of potential therapeutic targets and the validation of new drug candidates.

Compared to traditional gene knockout methods, our ZDHHC20 Gene Knockout Cell Lines offer a more streamlined, efficient, and reliable means for genetic manipulation with a high rate of specificity. Researchers can benefit from reduced off-target effects and superior reproducibility, contributing to more robust experimental outcomes.

The value of these cell lines lies not only in their ability to enhance our understanding of gene function but also in their potential to accelerate the development of novel therapeutics. By utilizing models that accurately replicate the absence of specific gene functions, users can significantly expedite their research timelines and improve the quality of their findings.

With a strong foundation in genetic engineering and cellular biology, our company is dedicated to providing high-quality, innovative products that meet the evolving needs of the scientific community. Our commitment to excellence ensures that researchers have the tools they need to advance their studies and achieve groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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