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ZDHHC17 Knockout Cell Lines

Gene: ZDHHC17

Official Full Name: zDHHC palmitoyltransferase 17provided by HGNC

Gene Summary: Enables identical protein binding activity and protein-cysteine S-palmitoyltransferase activity. Involved in lipoprotein transport; protein palmitoylation; and regulation of programmed cell death. Located in Golgi membrane and Golgi-associated vesicle membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29341 ZDHHC17 Knockout cell line (HeLa) Human ZDHHC17 1:3~1:6 Negative Online Inquiry
KO29342 ZDHHC17 Knockout cell line (HCT 116) Human ZDHHC17 1:2~1:4 Negative Online Inquiry
KO29343 ZDHHC17 Knockout cell line (HEK293) Human ZDHHC17 1:3~1:6 Negative Online Inquiry
KO29344 ZDHHC17 Knockout cell line (A549) Human ZDHHC17 1:3~1:4 Negative Online Inquiry

Background

ZDHHC17 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the functional study of the ZDHHC17 gene, which encodes a member of the ZDHHC family of palmitoyltransferases. These cell lines have been meticulously developed to have the ZDHHC17 gene rendered non-functional through a gene knockout approach, effectively allowing researchers to investigate the role of ZDHHC17 in various physiological and pathological processes.

The key function of ZDHHC17 involves the post-translational modification known as palmitoylation, a critical process that influences protein localization, stability, and interaction with other biomolecules. By using the knockout cell lines, researchers can explore the downstream effects of ZDHHC17 absence, shedding light on its contributions to cell signaling pathways, membrane dynamics, and the overall regulation of cellular functions.

The scientific importance of these knockout cell lines is vast, particularly in research settings focused on neurological disorders, cancer biology, and other diseases linked to dysregulated palmitoylation. ZDHHC17 has been implicated in the modulation of synaptic functions and neuronal health, making these cell lines valuable for drug discovery and therapeutic development aimed at restoring palmitoylation processes.

Compared to traditional wild-type cell lines, the ZDHHC17 Gene Knockout Cell Lines offer unique advantages, including a precise understanding of gene function, enhanced reproducibility in experimental results, and the elimination of confounding variables associated with gene expression variability. Researchers can thus obtain clearer insights into the specific contributions of ZDHHC17 in various biological contexts.

For researchers and clinicians aiming to delve deeper into gene function and its implications in health and disease, the availability of ZDHHC17 Gene Knockout Cell Lines represents a crucial tool for advancing scientific knowledge and therapeutic strategies. Our company specializes in providing high-quality biological products and leverages cutting-edge genetic engineering technologies to meet the evolving needs of the scientific community, ensuring our clients have the resources necessary for innovative research.

Please note that all services are for research use only. Not intended for any clinical use.

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