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ZDHHC12 Knockout Cell Lines

Gene: ZDHHC12

Official Full Name: zDHHC palmitoyltransferase 12provided by HGNC

Gene Summary: Enables protein-cysteine S-palmitoyltransferase activity. Involved in gephyrin clustering involved in postsynaptic density assembly; negative regulation of NLRP3 inflammasome complex assembly; and protein palmitoylation. Located in Golgi apparatus and endoplasmic reticulum. Is active in dendritic spine. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24559 ZDHHC12 Knockout cell line (HeLa) Human ZDHHC12 1:3~1:6 Negative Online Inquiry
KO24560 ZDHHC12 Knockout cell line (HCT 116) Human ZDHHC12 1:2~1:4 Negative Online Inquiry
KO24561 ZDHHC12 Knockout cell line (HEK293) Human ZDHHC12 1:3~1:6 Negative Online Inquiry
KO24562 ZDHHC12 Knockout cell line (A549) Human ZDHHC12 1:3~1:4 Negative Online Inquiry

Background

ZDHHC12 Gene Knockout Cell Lines are meticulously engineered cell lines where the ZDHHC12 gene, integral to various cellular processes, has been inactivated through targeted gene editing techniques such as CRISPR/Cas9. This product enables researchers to investigate the physiological role of ZDHHC12 in various biological contexts, particularly its influence on lipid metabolism, cell signaling, and signal transduction pathways. By eliminating this gene, scientists can observe resultant phenotypic changes, elucidating ZDHHC12's functions in human health and disease.

These knockout cell lines facilitate numerous experimental applications, including drug discovery, toxicity assessments, and the validation of genetic functions. The absence of the ZDHHC12 protein provides a unique model system to dissect the molecular mechanisms underlying its biological roles in conditions such as metabolic disorders, cancer, and neurodegenerative diseases. With the capacity to enhance research outcomes, these cell lines significantly contribute to advancing the field of molecular biology and therapeutic development.

Compared to traditional methods of gene silencing, such as RNA interference, ZDHHC12 Gene Knockout Cell Lines offer a permanent and specific solution without off-target effects often associated with alternative techniques. This specificity ensures precision in experimental design, leading to more reliable and reproducible results.

For researchers and clinicians seeking to deepen their understanding of gene function or explore the therapeutic potential of ZDHHC12 modulation, our product stands out for its robustness and simplicity of use. By harnessing these knockout cell lines, users benefit from a reliable and efficient platform that accelerates discovery and innovation.

Our company boasts extensive expertise in the production of high-quality biological products, ensuring that researchers have access to cutting-edge tools that propel their scientific inquiries. Our dedication to excellence and innovative research solutions positions us as a leader in the field of genetic engineering and cell line development.

Please note that all services are for research use only. Not intended for any clinical use.

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