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ZBTB6 Knockout Cell Lines

Gene: ZBTB6

Official Full Name: zinc finger and BTB domain containing 6provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31547 ZBTB6 Knockout cell line (HeLa) Human ZBTB6 1:3~1:6 Negative Online Inquiry
KO31548 ZBTB6 Knockout cell line (HCT 116) Human ZBTB6 1:2~1:4 Negative Online Inquiry
KO31549 ZBTB6 Knockout cell line (HEK293) Human ZBTB6 1:3~1:6 Negative Online Inquiry
KO31550 ZBTB6 Knockout cell line (A549) Human ZBTB6 1:3~1:4 Negative Online Inquiry

Background

ZBTB6 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functional role of the ZBTB6 gene, a transcriptional repressor involved in various biological processes, including immune regulation and cellular differentiation. These cell lines are generated using cutting-edge CRISPR/Cas9 technology, effectively disrupting the ZBTB6 gene and enabling researchers to investigate the gene's contributions to cellular functions and disease mechanisms.

The primary function of ZBTB6 is to regulate gene expression by binding to specific DNA sequences, influencing cellular pathways critical for immune responses and hematopoiesis. By creating knockout models, users can elucidate the effects of ZBTB6 loss on gene expression profiles, cellular proliferation, and differentiation patterns. Such insights are crucial for understanding diseases where ZBTB6 misregulation is implicated, including various cancers and autoimmune disorders.

The scientific importance of these cell lines lies in their application across numerous research domains, particularly in oncology and immunology. These models facilitate the examination of ZBTB6's role in disease progression and treatment responses, making them invaluable for preclinical studies and drug development. Furthermore, ZBTB6 Gene Knockout Cell Lines offer a standardized approach for replicable results, enhancing the reliability of research findings.

Compared to alternative models, such as wild-type or overexpression systems, knockout cell lines provide a direct assessment of ZBTB6 functionality, allowing for unequivocal interpretations of gene loss effects. This specificity minimizes background noise from compensatory mechanisms that might obscure experimental outcomes in other models.

The value of ZBTB6 Gene Knockout Cell Lines to researchers and clinicians resides in their precision and versatility. With these tools, users can drive innovative discoveries that could lead to novel therapeutic strategies and biomarker identification. By deeply engaging in critical cellular processes, ZBTB6 knockout models represent a robust platform for advancing our understanding of complex biological systems.

In addition, our company leverages extensive expertise in genetic engineering and cell line development to provide high-quality biological products, ensuring our clients have access to the most reliable research tools for their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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