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ZBTB34 Knockout Cell Lines

Gene: ZBTB34

Official Full Name: zinc finger and BTB domain containing 34provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21307 ZBTB34 Knockout cell line (HeLa) Human ZBTB34 1:3~1:6 Negative Online Inquiry
KO21308 ZBTB34 Knockout cell line (HCT 116) Human ZBTB34 1:2~1:4 Negative Online Inquiry
KO21309 ZBTB34 Knockout cell line (HEK293) Human ZBTB34 1:3~1:6 Negative Online Inquiry
KO21310 ZBTB34 Knockout cell line (A549) Human ZBTB34 1:3~1:4 Negative Online Inquiry

Background

ZBTB34 Gene Knockout Cell Lines are engineered cellular models that have been specifically designed to study the function and regulation of the ZBTB34 gene, a member of the zinc finger and BTB domain-containing protein family. These knockout cell lines have been created using CRISPR-Cas9 technology, allowing for precise and efficient gene editing to produce cells lacking functional ZBTB34 protein.

The primary function of these cell lines is to facilitate the investigation of ZBTB34's biological roles, including its involvement in transcriptional regulation, cell differentiation, and immune response modulation. Through various assays, researchers can observe phenotypic changes and altered signaling pathways that occur when ZBTB34 is ablated, thus elucidating its contribution to various physiological and pathological processes. This knowledge is critical in advancing our understanding of diseases, particularly cancers and autoimmune disorders where ZBTB34 may play a significant role.

In research contexts, ZBTB34 Gene Knockout Cell Lines are invaluable tools for dissecting the gene's function and potential therapeutic targets. Their precise genetic alterations enable researchers to conduct high-throughput screening, drug discovery, and functional studies, providing insights that are difficult to glean from wild-type lines. Compared to alternative models, such as transient knockdowns, these stable knockout lines offer greater consistency and reproducibility in experimental outcomes.

The specific advantages of ZBTB34 Gene Knockout Cell Lines include the ability to maintain the knockout phenotype across multiple generations and varied experimental conditions, ensuring that results are not skewed by transient gene expression effects. This robustness allows for more rigorous experimental designs and reliable interpretation of data, making them a preferred choice for leading laboratories.

For researchers and clinicians looking to deepen their knowledge of gene functions, these knockout cell lines represent a critical resource that can drive innovations in basic and applied sciences. They provide a pathway for discovering potential therapeutic interventions targeting ZBTB34-related pathways. Our company specializes in cutting-edge biotechnological solutions, offering expertly validated products backed by extensive research and development efforts, ensuring that you receive top-tier materials to support your scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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