Gene: ZBTB25
Official Full Name: zinc finger and BTB domain containing 25provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34695 | ZBTB25 Knockout cell line (HeLa) | Human | ZBTB25 | 1:3~1:6 | Negative | Online Inquiry |
KO34696 | ZBTB25 Knockout cell line (HCT 116) | Human | ZBTB25 | 1:2~1:4 | Negative | Online Inquiry |
KO34697 | ZBTB25 Knockout cell line (HEK293) | Human | ZBTB25 | 1:3~1:6 | Negative | Online Inquiry |
KO34698 | ZBTB25 Knockout cell line (A549) | Human | ZBTB25 | 1:3~1:4 | Negative | Online Inquiry |
ZBTB25 Gene Knockout Cell Lines are specially engineered cell lines created to facilitate the functional analysis of the ZBTB25 gene, a critical regulator implicated in various cellular processes such as differentiation, proliferation, and immune response modulation. These knockout cell lines have undergone precise genetic manipulation techniques, such as CRISPR-Cas9, to create a complete loss of function of the ZBTB25 gene, providing researchers with invaluable tools for dissecting its role in biological pathways.
The primary function of ZBTB25 Gene Knockout Cell Lines lies in enabling the study of gene function through phenotypic characterization. By observing the differences in cellular behavior between wild-type and ZBTB25 knockout cells, researchers can elucidate the gene's contributions to critical processes, such as cell cycle regulation and immune system response. This allows for greater insights into the gene's potential implications in diseases, including cancer and autoimmune disorders, as well as its role in normal cellular physiology.
The scientific importance of these cell lines extends to both basic and applied research domains. In clinical settings, ZBTB25 knockout cells can serve as models for drug discovery and testing, enabling scientists to identify potential therapeutic targets and evaluate drug efficacy in customized experiments. Furthermore, by providing a controlled environment to study gene knockouts, researchers can replicate specific pathophysiological conditions, enhancing the relevance of their findings.
Compared to alternative models such as transient transfection or use of broad-spectrum gene silencing methods, ZBTB25 Gene Knockout Cell Lines offer stable gene ablation, ensuring reproducibility and reliability of experimental results. This consistency is particularly beneficial for longitudinal studies where the effects of ZBTB25 loss-of-function can be meticulously tracked over time, ultimately leading to more robust data.
For researchers, clinicians, and pharmaceutical developers, ZBTB25 Gene Knockout Cell Lines represent a pivotal advancement in the investigational toolkit, enabling deeper insights into gene function while supporting the development of novel therapeutics. Our company boasts a solid foundation in genetic engineering and cell line development, ensuring that our products meet rigorous scientific standards while fulfilling the exacting needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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