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YIF1B Knockout Cell Lines

Gene: YIF1B

Official Full Name: Yip1 interacting factor homolog B, membrane trafficking proteinprovided by HGNC

Gene Summary: Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23724 YIF1B Knockout cell line (HeLa) Human YIF1B 1:3~1:6 Negative Online Inquiry
KO23725 YIF1B Knockout cell line (HCT 116) Human YIF1B 1:2~1:4 Negative Online Inquiry
KO23726 YIF1B Knockout cell line (HEK293) Human YIF1B 1:3~1:6 Negative Online Inquiry
KO23727 YIF1B Knockout cell line (A549) Human YIF1B 1:3~1:4 Negative Online Inquiry

Background

YIF1B Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically created to lack the expression of the YIF1B gene, a critical player in various cellular processes including vesicular transport and cellular response to stress. By utilizing CRISPR-Cas9 technology, these cell lines enable researchers to study the biological implications of YIF1B deficiency in both physiological and pathological contexts. The disruption of this gene provides a robust platform to investigate its role in cellular homeostasis, immune response, and potential involvement in diseases such as cancer and neurodegeneration.

The primary function of YIF1B is to regulate endoplasmic reticulum-Golgi transport, making it an essential factor influencing protein processing and secretion. By knocking out YIF1B, scientists can directly observe the resulting alterations in intracellular trafficking pathways and assess the impact on cell signaling and metabolism. This functionality extends to the analysis of gene function, drug screening, and the validation of therapeutic targets in clinical studies.

In terms of scientific importance, YIF1B gene knockout cell lines serve as a valuable resource for elucidating the molecular mechanisms underlying various diseases. These cell lines can be utilized in research to screen for potential drug candidates, as they allow for the examination of how YIF1B deficiency affects drug efficacy and metabolism. This knowledge is pivotal in developing targeted therapies that can enhance treatment outcomes.

Compared to traditional cell lines, the YIF1B knockout models offer a unique advantage of specificity. While some cell lines may exhibit endogenous levels of YIF1B, leading to potential confounding results, these knockout variants provide a clean slate for in-depth functional analysis. Furthermore, the high efficiency of CRISPR technology employed in their creation ensures that researchers obtain consistent and reproducible results.

For researchers and clinicians focused on cellular mechanisms, drug discovery, or understanding disease pathophysiology, YIF1B Gene Knockout Cell Lines present an invaluable tool. They not only facilitate the investigation of the YIF1B pathway but also support the broader scientific community in unraveling complex biological processes.

Our company specializes in the production and characterization of innovative genetic models, with a strong commitment to supporting cutting-edge research through high-quality biological products. With a dedicated team of experts and state-of-the-art facilities, we strive to provide resources that empower scientists to advance their research and clinical goals effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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