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XNDC1N Knockout Cell Lines

Gene: XNDC1N

Official Full Name: XRCC1 N-terminal domain containing 1, N-terminal likeprovided by HGNC

Gene Summary: Predicted to enable damaged DNA binding activity. Predicted to be involved in single strand break repair. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12562 XNDC1N Knockout cell line (HeLa) Human XNDC1N 1:3~1:6 Negative Online Inquiry
KO12563 XNDC1N Knockout cell line (HCT 116) Human XNDC1N 1:2~1:4 Negative Online Inquiry
KO12564 XNDC1N Knockout cell line (HEK293) Human XNDC1N 1:3~1:6 Negative Online Inquiry
KO12565 XNDC1N Knockout cell line (A549) Human XNDC1N 1:3~1:4 Negative Online Inquiry

Background

XNDC1N Gene Knockout Cell Lines represent a pivotal advancement in gene editing technology, specifically designed to facilitate the study of gene function and gene-targeted therapies. These cell lines have been meticulously engineered to exhibit a complete knockout of the XNDC1N gene, allowing researchers to investigate the biological roles and pathways influenced by this gene without its expression.

The primary mechanism by which the XNDC1N Gene Knockout Cell Lines function involves the utilization of CRISPR-Cas9 technology, ensuring precise alterations to the genomic sequence. This advanced editing technique introduces double-strand breaks at specific locations within the XNDC1N gene, leading to its interruption and subsequent non-expression. The resultant knockout phenotype enables researchers to observe and analyze cellular responses, signaling cascades, and compensatory mechanisms that may arise as a result of the gene's absence.

From a scientific perspective, these cell lines are invaluable in the realms of gene function discovery, disease modeling, and drug screening. They provide researchers with a robust platform to explore the implications of XNDC1N in various biological processes, including cell proliferation, differentiation, and apoptosis. Additionally, in clinical research settings, these knockout models can aid in understanding pathogenic mechanisms linked to certain diseases, paving the way for the identification of new therapeutic targets.

Compared to alternative methods, such as transient transfection or RNA interference, the use of XNDC1N Gene Knockout Cell Lines offers long-term stability and unequivocal gene disruption. These cell lines are particularly advantageous for investigations that require consistent and reproducible outcomes over extended periods, thereby minimizing variability associated with transient expression techniques.

The value of XNDC1N Gene Knockout Cell Lines extends beyond their technical merits; they represent a critical tool for researchers and clinicians aiming to unlock the complexities of gene regulation and its implications in health and disease. The ability to conduct thorough investigations with precision and reliability is essential for advancing scientific knowledge and therapeutic innovations.

Our company specializes in providing high-quality biological products with a focus on advanced gene editing technologies. With a commitment to supporting the research community, we aim to empower scientists with tools that enhance their exploration of genetic pathways and contribute to breakthroughs in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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