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WNT7B Knockout Cell Lines

Gene: WNT7B

Official Full Name: Wnt family member 7Bprovided by HGNC

Gene Summary: This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11616 WNT7B Knockout cell line (HeLa) Human WNT7B 1:3~1:6 Negative Online Inquiry
KO11617 WNT7B Knockout cell line (HCT 116) Human WNT7B 1:2~1:4 Negative Online Inquiry
KO11618 WNT7B Knockout cell line (HEK293) Human WNT7B 1:3~1:6 Negative Online Inquiry
KO11619 WNT7B Knockout cell line (A549) Human WNT7B 1:3~1:4 Negative Online Inquiry

Background

WNT7B Gene Knockout Cell Lines are genetically engineered cell lines specifically developed to disable the WNT7B gene, a key component in the Wnt signaling pathway, which plays a crucial role in cellular processes such as differentiation, proliferation, and stem cell maintenance. By utilizing CRISPR-Cas9 technology or similar gene editing techniques, these cell lines facilitate the effective study of the functional consequences of WNT7B gene deletion, allowing researchers to delve into its impact on various biological processes and diseases.

The primary mechanisms of action involve the disruption of WNT signaling pathways, which are integral in developmental biology and tumorigenesis. The absence of WNT7B can lead to substantial changes in cellular behavior and gene expression, providing a powerful tool for understanding its role in development, cancer, and other related pathologies. This makes WNT7B knockout models particularly valuable in pharmacological studies, cancer research, and regenerative medicine.

In scientific research, these knockout cell lines offer invaluable insights into the dynamics of cell signaling and potentially reveal novel therapeutic targets. Compared to traditional methodologies, such as RNA interference or chemical inhibitors, which may yield transient or non-specific effects, our WNT7B Gene Knockout Cell Lines provide a stable and permanent modification that ensures consistent results for long-term studies.

Researchers and clinicians benefit from the specificity and reliability of these knockout models, allowing for more accurate modeling of diseases and enhancing translational research. The precise gene targeting ensures high fidelity in experimental reproducibility, making these cell lines an essential asset in any biological research laboratory.

At our company, we pride ourselves on our deep expertise in genetic engineering and commitment to advancing biological research tools. We are dedicated to providing researchers with high-quality, reliable resources like the WNT7B Gene Knockout Cell Lines, enabling innovative discoveries and advancements in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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