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WFDC11 Knockout Cell Lines

Gene: WFDC11

Official Full Name: WAP four-disulfide core domain 11provided by HGNC

Gene Summary: This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12600 WFDC11 Knockout cell line (HeLa) Human WFDC11 1:3~1:6 Negative Online Inquiry

Background

WFDC11 Gene Knockout Cell Lines are specifically engineered cellular models in which the WFDC11 gene has been disrupted through targeted genome editing techniques, such as CRISPR-Cas9. The WFDC11 gene encodes for a protein involved in various biological processes, including modulation of immune responses and cellular signaling pathways. By establishing knockout cell lines, researchers can gain insights into the gene's function, elucidate its roles in health and disease, and assess its impact on cellular behavior.

These specialized cell lines function by providing a controlled environment in which the absence of WFDC11 allows for the study of compensatory mechanisms, gene interactions, and signaling pathways that might be obscured in wild-type cells. By comparing WFDC11 knockout cells to their wild-type counterparts, investigators can identify distinct phenotypic changes, such as altered cell proliferation, migration, or apoptosis, thereby enhancing our understanding of the gene's contributions to specific biological contexts and disease states.

The scientific importance of WFDC11 Gene Knockout Cell Lines extends to their applications in both basic and applied research. Clinically, these models can facilitate drug discovery and development by enabling researchers to explore the therapeutic implications of targeting the WFDC11-associated pathways. In basic research, they serve as invaluable tools for dissecting complex biological networks and investigating gene function, which is crucial for advancing precision medicine.

One of the distinct advantages of using WFDC11 Gene Knockout Cell Lines is their high specificity and reliability, enabling researchers to perform reproducible experiments with clear outcomes. Unlike traditional knockdown approaches that rely on transient RNA interference, knockout cell lines provide a stable genetic alteration, ensuring consistent characteristics throughout experimental procedures. This stability is essential for long-term studies and validation.

For researchers and clinicians alike, these cell lines represent a powerful resource for advancing scientific knowledge and developing novel therapeutic strategies. The potential applications in drug efficacy testing, biomarker identification, and understanding disease pathogenesis underscore their value and versatility.

Our company, with a robust background in genomic engineering and cell biology, is committed to providing high-quality biological products. We ensure that our WFDC11 Gene Knockout Cell Lines are meticulously characterized and validated to meet the rigorous standards of modern research, empowering scientists to push the boundaries of biological discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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