Gene: WDR53
Official Full Name: WD repeat domain 53provided by HGNC
Gene Summary: This gene encodes a protein containing WD domains. The function of this gene is unknown. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12606 | WDR53 Knockout cell line (HeLa) | Human | WDR53 | 1:3~1:6 | Negative | Online Inquiry |
KO12607 | WDR53 Knockout cell line (HCT 116) | Human | WDR53 | 1:2~1:4 | Negative | Online Inquiry |
KO12608 | WDR53 Knockout cell line (HEK293) | Human | WDR53 | 1:3~1:6 | Negative | Online Inquiry |
KO12609 | WDR53 Knockout cell line (A549) | Human | WDR53 | 1:3~1:4 | Negative | Online Inquiry |
WDR53 Gene Knockout Cell Lines are genetically engineered cell lines specifically created to lack the expression of the WDR53 gene, which plays a crucial role in various cellular processes such as DNA damage response and cell cycle regulation. The knockout of this gene is achieved using advanced CRISPR-Cas9 technology, which allows precise alterations in the genomic DNA of the cell lines. By effectively knocking out the WDR53 gene, researchers can study the functional consequences of its absence, providing insights into its role in cellular homeostasis, tumorigenesis, and potential therapeutic targets.
The primary mechanism of action in these cell lines revolves around the loss of WDR53 function, leading to alterations in cellular pathways such as stress response and apoptosis. This experimental model is invaluable for elucidating the gene's contribution to important cellular processes and disease mechanisms. Importantly, WDR53 has been implicated in cancer biology, making these cell lines significant tools for cancer research, drug discovery, and assessing therapeutic strategies involving DNA repair mechanisms.
Compared to conventional cell lines, the WDR53 Gene Knockout Cell Lines offer distinct advantages, including high specificity for studying the gene's effects without the complications of functional redundancy and compensatory pathways that can arise in non-knockout models. This specificity enhances the reliability of experimental data and facilitates more precise interpretations of results.
For researchers and clinicians, the availability of WDR53 Gene Knockout Cell Lines accelerates the process of understanding disease mechanisms, fostering innovations in targeted therapies and biomarker discovery. With this high-quality product, our company leverages its extensive expertise in genetic engineering and cell biology to provide researchers with reliable tools that empower groundbreaking studies. Our commitment to precision and scientific excellence ensures that these cell lines are produced with the utmost quality, supporting advancements in both basic research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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