Gene: WDR47
Official Full Name: WD repeat domain 47provided by HGNC
Gene Summary: Predicted to act upstream of or within several processes, including detection of hot stimulus involved in thermoception; neuronal stem cell population maintenance; and telencephalon development. Predicted to be located in several cellular components, including growth cone; microtubule; and neuronal cell body. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30150 | WDR47 Knockout cell line (HeLa) | Human | WDR47 | 1:3~1:6 | Negative | Online Inquiry |
KO30151 | WDR47 Knockout cell line (HCT 116) | Human | WDR47 | 1:2~1:4 | Negative | Online Inquiry |
KO30152 | WDR47 Knockout cell line (HEK293) | Human | WDR47 | 1:3~1:6 | Negative | Online Inquiry |
KO30153 | WDR47 Knockout cell line (A549) | Human | WDR47 | 1:3~1:4 | Negative | Online Inquiry |
WDR47 Gene Knockout Cell Lines are genetically modified cell lines that have had the WDR47 gene disrupted to study its functional role and implications specifically in cellular processes. The WDR47 gene encodes a protein that is thought to play a critical role in various cellular pathways, including those involved in cell signaling and response to stress. By creating knockout cell lines, researchers can observe the changes in cellular behavior and pathway activation resulting from the absence of WDR47, thereby elucidating its biological importance.
The primary mechanism through which these knockout cell lines operate is the use of CRISPR-Cas9 technology to introduce targeted mutations that result in the complete loss of WDR47 expression. This approach enables researchers to assess the phenotypic consequences of gene inactivation in a controlled environment. Investigating gene function through these models provides crucial insights into the molecular pathways that WDR47 influences, as well as its potential involvement in diseases such as cancer and neurodegenerative disorders.
The scientific significance of WDR47 Gene Knockout Cell Lines lies in their potential applications in both academic and clinical research, particularly in drug discovery and genetic studies. By understanding the role of WDR47, researchers can identify new therapeutic targets or biomarkers. Compared to traditional methods of gene knockdown, our knockout cell lines offer a permanent and stable alteration of gene function, allowing for long-term studies and more robust data.
One of the key advantages of our product is the thorough validation process it has undergone, ensuring high efficiency and specificity in gene disruption. This reliability, coupled with our commitment to providing comprehensive support and documentation, makes WDR47 Gene Knockout Cell Lines an irresistible choice for researchers seeking to advance their studies in genetics and cell biology.
At our company, we pride ourselves on our deep expertise in genetic engineering and our commitment to supplying high-quality biological research tools. WDR47 Gene Knockout Cell Lines exemplify our dedication to empowering the scientific community to unlock the complexities of gene function and improve health outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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