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WDR44 Knockout Cell Lines

Gene: WDR44

Official Full Name: WD repeat domain 44provided by HGNC

Gene Summary: This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat binds the GTP-containing active form of rab11. This protein may play a role in endosome recycling. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21648 WDR44 Knockout cell line (HeLa) Human WDR44 1:3~1:6 Negative Online Inquiry
KO21649 WDR44 Knockout cell line (HCT 116) Human WDR44 1:2~1:4 Negative Online Inquiry
KO21650 WDR44 Knockout cell line (HEK293) Human WDR44 1:3~1:6 Negative Online Inquiry
KO21651 WDR44 Knockout cell line (A549) Human WDR44 1:3~1:4 Negative Online Inquiry

Background

WDR44 Gene Knockout Cell Lines are advanced biological tools created to facilitate in-depth studies of gene function and cellular processes related to the WDR44 gene. These cell lines have been genetically modified to provide a complete knockout of the WDR44 gene, allowing researchers to scrutinize the physiological implications of its absence in a controlled environment. WDR44 is implicated in various cellular functions, including cellular growth, apoptosis, and gene regulation, making the knockout model a powerful instrument for dissecting its roles in health and disease.

The primary mechanism of action in these knockout cell lines arises from CRISPR-Cas9 technology, which effectively introduces targeted edits in the genomic DNA, disabling the WDR44 gene expression. This innovative approach enables precise validation of gene function, paving the way for exploration into pathways that WDR44 may influence, including cell cycle regulation and responses to stress signals.

The scientific importance of WDR44 Gene Knockout Cell Lines extends to both basic research and clinical applications. In research settings, these models can contribute to a better understanding of cancer biology, neurodegenerative conditions, and cellular stress responses, potentially leading to the identification of novel therapeutic targets. Clinicians can utilize these cell lines to assess the role of WDR44 in various diseases, applying findings to improve treatment strategies and patient outcomes.

One of the standout advantages of our WDR44 Gene Knockout Cell Lines is their exceptional reliability and reproducibility. Compared to alternative models, such as transient knockdowns or less precise genetic modifications, our cell lines provide a stable platform for long-term experiments, ensuring that the results are both consistent and significant. Researchers can achieve a higher degree of confidence in their data, which is a crucial aspect in the competitive field of biomedical research.

Ultimately, WDR44 Gene Knockout Cell Lines represent a valuable addition to the toolkit of researchers and clinicians focused on unraveling the complexities of cell biology and developing innovative therapies. By leveraging our extensive expertise in gene editing technologies, coupled with a commitment to high-quality product development, we are dedicated to empowering scientific discovery and advancing the frontiers of genetic research.

Please note that all services are for research use only. Not intended for any clinical use.

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