Gene: WDR37
Official Full Name: WD repeat domain 37provided by HGNC
Gene Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30197 | WDR37 Knockout cell line (HeLa) | Human | WDR37 | 1:3~1:6 | Negative | Online Inquiry |
KO30198 | WDR37 Knockout cell line (HCT 116) | Human | WDR37 | 1:2~1:4 | Negative | Online Inquiry |
KO30199 | WDR37 Knockout cell line (HEK293) | Human | WDR37 | 1:3~1:6 | Negative | Online Inquiry |
KO30200 | WDR37 Knockout cell line (A549) | Human | WDR37 | 1:3~1:4 | Negative | Online Inquiry |
WDR37 Gene Knockout Cell Lines are innovative model systems specifically engineered to facilitate the study of the WDR37 gene's function in various biological processes. Utilizing CRISPR-Cas9 gene-editing technology, these cell lines exhibit complete ablation of the WDR37 gene, enabling researchers to examine the cellular pathways and mechanisms influenced by its absence. The knockout of WDR37 serves as a critical tool for investigating its role in cellular processes such as signaling, proliferation, and apoptosis, among others.
The key mechanism behind the effectiveness of these cell lines lies in their ability to mimic the physiological conditions of WDR37 deficiency, thus providing insights into the gene's involvement in gene regulation and protein interactions. This functional analysis is invaluable for determining the implications of WDR37 in diseases, potentially highlighting targets for therapeutic intervention.
In both research and clinical settings, WDR37 Gene Knockout Cell Lines offer significant scientific value. They are essential for elucidating the molecular underpinnings of various disorders, such as cancer or metabolic syndromes, where WDR37's role may be critical. Moreover, their application in high-throughput screening allows for the rapid identification of compounds that can modulate the pathways impacted by WDR37.
Compared to traditional cell lines, the WDR37 knockout variants provide a unique advantage by offering a clearer representation of the gene's loss-of-function effects. Unlike standard models that may retain partial gene activity, these knockout cell lines present a more accurate environment for studying gene-to-function relationships.
For researchers and clinicians aiming to advance their understanding of gene function in complex biological systems, WDR37 Gene Knockout Cell Lines are indispensable. They empower users to generate reproducible and relevant data that can drive innovative approaches in gene therapy and molecular medicine.
With a strong commitment to advancing cellular research, our company prides itself on providing high-quality, rigorously validated biological products. Our extensive expertise in genetic engineering ensures that WDR37 Gene Knockout Cell Lines are robust tools for forward-thinking researchers dedicated to unlocking the mysteries of gene function.
Please note that all services are for research use only. Not intended for any clinical use.
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