Gene: WDR27
Official Full Name: WD repeat domain 27provided by HGNC
Gene Summary: This gene encodes a protein with multiple WD repeats. Proteins with these repeats may form scaffolds for protein-protein interaction and play key roles in cell signalling. Alternative splicing results in multiple transcript variants, but the full-length structure of some of these variants cannot be determined. [provided by RefSeq, Nov 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21210 | WDR27 Knockout cell line (HeLa) | Human | WDR27 | 1:3~1:6 | Negative | Online Inquiry |
KO21211 | WDR27 Knockout cell line (HCT 116) | Human | WDR27 | 1:2~1:4 | Negative | Online Inquiry |
KO21212 | WDR27 Knockout cell line (HEK293) | Human | WDR27 | 1:3~1:6 | Negative | Online Inquiry |
KO21213 | WDR27 Knockout cell line (A549) | Human | WDR27 | 1:3~1:4 | Negative | Online Inquiry |
WDR27 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, designed to facilitate research into the functional roles of the WDR27 gene in various cellular processes. These engineered cell lines have been developed through sophisticated gene editing techniques, specifically CRISPR/Cas9 technology, which allows for precise modifications in the genome. By knocking out the WDR27 gene, researchers can study its influence on cellular processes such as proliferation, differentiation, and apoptosis, providing insights into its role in health and disease.
The functionality of WDR27 Gene Knockout Cell Lines lies in their ability to reveal the consequences of WDR27 gene disruption. When the gene is knocked out, researchers can observe changes at phenotypic, transcriptomic, and proteomic levels, thus elucidating the signaling pathways and biological mechanisms that are influenced by this gene. This makes the cell lines invaluable for both basic and applied research, particularly in studies involving cancer biology, neurodevelopmental disorders, and metabolic diseases.
The scientific importance of these cell lines extends to their applications in drug discovery and therapeutic interventions. By offering insights into the molecular mechanisms governed by WDR27, researchers can identify potential drug targets and biomarkers for disease progression. Furthermore, the specificity of gene knockout reduces off-target effects that can complicate the interpretation of results, distinguishing these cell lines from traditional models.
Compared to alternatives such as RNA interference models or chemical inhibitors, WDR27 Gene Knockout Cell Lines provide a more stable, long-term solution for in-depth genetic studies. The knockout approach offers a permanent alteration in the genetic makeup, allowing for reproducibility and reliability in experimental design.
For researchers and clinicians, the value of WDR27 Gene Knockout Cell Lines is immense. These tools not only enhance the understanding of fundamental biological processes but also pave the way for innovative therapeutic strategies. By employing these cell lines, users can accelerate their research in a well-defined manner, potentially leading to breakthroughs in the treatment of conditions linked to the WDR27 gene.
Our company is committed to advancing scientific research through the provision of high-quality biological products. With expertise in gene editing and a portfolio of reliable cell lines, we empower researchers to unlock new insights into the molecular basis of health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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