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WDR13 Knockout Cell Lines

Gene: WDR13

Official Full Name: WD repeat domain 13provided by HGNC

Gene Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese. [provided by RefSeq, Nov 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07385 WDR13 Knockout cell line (HeLa) Human WDR13 1:3~1:6 Negative Online Inquiry
KO07386 WDR13 Knockout cell line (HCT 116) Human WDR13 1:2~1:4 Negative Online Inquiry
KO07387 WDR13 Knockout cell line (HEK293) Human WDR13 1:3~1:6 Negative Online Inquiry
KO07388 WDR13 Knockout cell line (A549) Human WDR13 1:3~1:4 Negative Online Inquiry

Background

WDR13 Gene Knockout Cell Lines are genetically modified cell lines in which the WDR13 gene has been inactivated or "knocked out" through advanced CRISPR-Cas9 technology. This product enables researchers to study the specific contributions of the WDR13 gene in various biological processes, such as metabolism, signal transduction, and cellular stress responses. By utilizing these knockout cell lines, scientists can elucidate the gene’s role in regulating critical pathways and assess how its absence affects cellular function and organismal physiology.

The primary function of WDR13 Gene Knockout Cell Lines involves the investigation of WDR13-related signaling pathways, particularly those associated with obesity and metabolic disorders. These cell lines provide an invaluable tool for assessing the biochemical and molecular changes arising from the lack of WDR13, allowing researchers to perform experiments to reveal the potential therapeutic targets for obesity and related diseases.

In the scientific community, the ability to create precise gene knockouts has become crucial for understanding genetic contributions to diseases at a molecular level. WDR13 Gene Knockout Cell Lines are particularly relevant in both fundamental research and potential clinical applications, such as drug discovery and testing therapies aimed at metabolic syndrome management. They bridge the gap between basic biology and translational research, facilitating the development of effective treatments.

The unique selling points of WDR13 Gene Knockout Cell Lines include their high specificity and reproducibility, which surpasses many conventional methods of gene manipulation. Unlike transient knockdown approaches, these stable knockout lines provide a consistent and reliable platform for long-term studies, enabling researchers to achieve deeper insights into gene functionality.

For researchers and clinicians focused on metabolic disorders, these knockout cell lines offer unparalleled value as they generate data crucial for understanding disease mechanisms and exploring novel therapeutic strategies. By investing in WDR13 Gene Knockout Cell Lines, users gain access to a robust system that enhances the understanding of genetic implications in disease.

Our company is dedicated to advancing scientific discovery through innovative biological products, ensuring the highest standards of research quality and reproducibility. Our expertise in genetic engineering and commitment to providing comprehensive solutions make us a trusted partner in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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