Gene: WASHC3
Official Full Name: WASH complex subunit 3provided by HGNC
Gene Summary: Predicted to be involved in actin filament polymerization and exocytosis. Part of WASH complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23188 | WASHC3 Knockout cell line (HeLa) | Human | WASHC3 | 1:3~1:6 | Negative | Online Inquiry |
KO23189 | WASHC3 Knockout cell line (HCT 116) | Human | WASHC3 | 1:2~1:4 | Negative | Online Inquiry |
KO23190 | WASHC3 Knockout cell line (HEK293) | Human | WASHC3 | 1:3~1:6 | Negative | Online Inquiry |
KO23191 | WASHC3 Knockout cell line (A549) | Human | WASHC3 | 1:3~1:4 | Negative | Online Inquiry |
WASHC3 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the WASHC3 gene, which encodes for a critical component of the Wiskott-Aldrich syndrome protein (WASP) family involved in actin polymerization and cellular trafficking. These cell lines serve as a vital tool for researchers investigating the role of WASHC3 in various cellular processes, including endocytosis, immune response, and cell motility. By disabling the WASHC3 gene, scientists can study the downstream effects on cellular dynamics and elucidate the biological pathways influenced by this protein.
The primary mechanism through which WASHC3 operates is by coordinating the activity of the actin cytoskeleton in response to intracellular signaling cues. As such, the knockout of WASHC3 provides remarkable insights into the dysfunctions that may lead to diseases characterized by aberrant cellular behaviors, such as cancer metastasis or immune system disorders. The scientific community recognizes the importance of these cell lines for both basic and applied research, as they enable the dissection of complex pathways and the development of targeted therapeutic strategies.
What sets WASHC3 Gene Knockout Cell Lines apart from traditional cell lines or other gene knockout methodologies is their specificity and reliability. Unlike transient knockdowns that may yield variable or inconsistent results, these stable knockout lines present a consistent baseline for experimental replication. Researchers benefit from high reproducibility in their findings, an essential aspect of robust scientific inquiry.
For clinicians and researchers alike, the value of WASHC3 Gene Knockout Cell Lines lies in their ability to provide unprecedented clarity into the roles of actin-associated proteins in health and disease. As laboratories increasingly seek more precise and innovative solutions to advance their studies, these cell lines represent a cutting-edge asset.
Our company brings a wealth of expertise in genetic engineering and cellular biology, ensuring that our products meet the highest standards of scientific integrity and performance. We are committed to empowering researchers with reliable tools that facilitate groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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