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VPS13C Knockout Cell Lines

Gene: VPS13C

Official Full Name: vacuolar protein sorting 13 homolog Cprovided by HGNC

Gene Summary: Involved in mitochondrion organization and negative regulation of type 2 mitophagy. Located in several cellular components, including late endosome; lipid droplet; and mitochondrial outer membrane. Implicated in Parkinson's disease 23. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12666 VPS13C Knockout cell line (HeLa) Human VPS13C 1:3~1:6 Negative Online Inquiry
KO12667 VPS13C Knockout cell line (HCT 116) Human VPS13C 1:2~1:4 Negative Online Inquiry
KO12668 VPS13C Knockout cell line (HEK293) Human VPS13C 1:3~1:6 Negative Online Inquiry
KO12669 VPS13C Knockout cell line (A549) Human VPS13C 1:3~1:4 Negative Online Inquiry

Background

VPS13C Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the VPS13C gene and associated biological processes. This product offers researchers a powerful tool to investigate the role of VPS13C in cellular functions, particularly its contributions to lipid metabolism, neurodegenerative diseases, and cellular trafficking mechanisms.

The key function of VPS13C knockout cell lines is to provide a platform for examining the effects of the absence of the VPS13C gene, thereby elucidating its biological functions. VPS13C is known to be involved in the transport of lipids between organelles, making it crucial for maintaining cellular homeostasis. Studies using these knockout lines can reveal mechanistic insights into how VPS13C mutations contribute to disease, notably in conditions such as Parkinson’s disease and other neurodegenerative disorders.

The scientific importance of VPS13C gene knockout cell lines is underscored by their application in both research and clinical settings. They enable high-throughput screening of potential therapeutic compounds aimed at modulating lipoprotein metabolism or restoring normal cellular function in VPS13C-related pathologies. Moreover, these cell lines are invaluable in studying gene function, identifying signaling pathways, and potentially paving the way for innovative treatment strategies.

One of the specific advantages of our VPS13C knockout cell lines is their precision in gene editing, which surpasses conventional alternatives that may introduce off-target effects. Our cells have been rigorously validated to ensure consistent and reproducible knockout of the VPS13C gene, providing researchers with reliable data essential for their studies.

The value of integrating VPS13C Gene Knockout Cell Lines into your research paradigm lies in their ability to illuminate fundamental biological questions and accelerate the development of interventions for related disorders. They empower researchers and clinicians to advance our understanding of complex cellular mechanisms and to design informed therapeutic approaches.

At [Your Company Name], we pride ourselves on our expertise in developing cutting-edge biological products that support the research community. With a focus on quality and innovation, our VPS13C Gene Knockout Cell Lines are the ideal choice for enhancing your exploration of cellular processes and disease mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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