Gene: VMAC
Official Full Name: vimentin type intermediate filament associated coiled-coil proteinprovided by HGNC
Gene Summary: Predicted to be located in cytoplasm. Predicted to be active in type III intermediate filament. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21426 | VMAC Knockout cell line (HeLa) | Human | VMAC | 1:3~1:6 | Negative | Online Inquiry |
KO21427 | VMAC Knockout cell line (HEK293) | Human | VMAC | 1:3~1:6 | Negative | Online Inquiry |
VMAC Gene Knockout Cell Lines are sophisticated biological tools designed for the precise study of gene function and regulation through the targeted disruption of specific genomic sequences. Utilizing advanced CRISPR-Cas9 technology, these cell lines provide researchers with a reliable means to inactivate genes of interest, enabling the exploration of their roles in various cellular processes, diseases, and developmental pathways.
The key functionality of VMAC Gene Knockout Cell Lines lies in their ability to facilitate gene editing at the DNA level. The CRISPR-Cas9 system employs a guide RNA to direct the Cas9 nuclease to the desired genomic location, where it creates a double-strand break. This break is then repaired by non-homologous end joining (NHEJ), a process that often results in insertions or deletions that disrupt gene function. This allows for the generation of knockout mutations that can be analyzed for phenotypic consequences, ultimately contributing to a deeper understanding of gene activity.
The scientific importance of these cell lines is evident in their wide-ranging applications across both research and clinical settings. They serve as vital models for investigating gene function in cancer biology, drug resistance, metabolic disorders, and neurobiology, among others. The ability to study pathophysiological mechanisms at the molecular level positions VMAC Gene Knockout Cell Lines as indispensable tools for advancing biomedical research and therapeutic development.
Compared to traditional gene knockout techniques, which can be time-consuming and less efficient, VMAC Gene Knockout Cell Lines offer a streamlined approach that enhances experimental reproducibility. Their established background in frequently used cellular systems reduces variability, while the precise nature of the gene editing allows for targeted investigations that generate more relevant data.
Researchers and clinicians will find great value in VMAC Gene Knockout Cell Lines due to their versatility and robust performance, making them an ideal choice for experimental designs aimed at deciphering complex biological questions. The efficacy and accuracy of these cell lines are complemented by our company’s extensive expertise in developing cutting-edge genetic tools and reagents for the scientific community, ensuring you have the best resources at your fingertips to further your research objectives.
Please note that all services are for research use only. Not intended for any clinical use.
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