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VBP1 Knockout Cell Lines

Gene: VBP1

Official Full Name: VHL binding protein 1provided by HGNC

Gene Summary: The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09698 VBP1 Knockout cell line (HeLa) Human VBP1 1:3~1:6 Negative Online Inquiry
KO09699 VBP1 Knockout cell line (HCT 116) Human VBP1 1:2~1:4 Negative Online Inquiry
KO09700 VBP1 Knockout cell line (HEK293) Human VBP1 1:3~1:6 Negative Online Inquiry
KO09701 VBP1 Knockout cell line (A549) Human VBP1 1:3~1:4 Negative Online Inquiry

Background

VBP1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate in-depth studies of the VBP1 gene's function and its downstream biological pathways. Utilizing CRISPR-Cas9 genome editing technology, these cell lines exhibit a complete knockout of the VBP1 gene, which plays a crucial role in various cellular processes, including stress response, metabolism, and apoptosis. By precisely eliminating the VBP1 gene, researchers can investigate the resulting phenotypic alterations and gain insights into the gene's contribution to normal cellular physiology and pathological conditions.

The primary mechanism by which VBP1 Gene Knockout Cell Lines operate revolves around the absence of VBP1 protein expression, allowing researchers to specifically assess the impacts of this loss on cellular behavior. These cell lines serve as valuable tools in unraveling the molecular underpinnings of diseases associated with VBP1 dysregulation, such as neurodegenerative disorders and cancer. In both basic and applied biomedical research, the utility of VBP1 knockout models extends to drug development, where the understanding of target pathways can lead to the design of more effective therapeutics.

What sets our VBP1 Gene Knockout Cell Lines apart from competitors is their high specificity and validation, ensuring that experiments yield reproducible and reliable results. Each cell line is rigorously characterized to confirm the knockout status and provide a robust background for downstream assays, including gene expression analysis, metabolic profiling, and drug response studies.

Researchers and clinicians will find exceptional value in these cell lines as they offer a unique opportunity to explore the intricacies of VBP1-related pathways in a controlled environment. Whether for basic research, translational studies, or drug development, these cell lines represent a powerful asset that can expedite discoveries and contribute to advancing scientific knowledge.

Our company prides itself on its commitment to providing high-quality biological products supported by extensive research and expertise. With a focus on innovation and a deep understanding of the needs of our customers, we aim to empower researchers around the globe with cutting-edge tools that drive scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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