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USP50 Knockout Cell Lines

Gene: USP50

Official Full Name: ubiquitin specific peptidase 50provided by HGNC

Gene Summary: Enables cysteine-type deubiquitinase activity. Involved in regulation of cell cycle G2/M phase transition. Acts upstream of or within several processes, including nuclear speck organization; positive regulation of NLRP3 inflammasome complex assembly; and positive regulation of macromolecule metabolic process. Located in centrosome; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20525 USP50 Knockout cell line (HCT 116) Human USP50 1:2~1:4 Negative Online Inquiry

Background

USP50 Gene Knockout Cell Lines are a specialized tool in molecular biology designed to facilitate genetic research by providing a unique platform for studying the function and regulation of the USP50 gene. These cell lines have been precisely engineered using CRISPR-Cas9 technology to create targeted gene knockouts, enabling researchers to investigate the biological roles of USP50 in cellular processes, signaling pathways, and disease mechanisms.

The primary function of USP50 is to encode a protein belonging to the ubiquitin-specific protease family, influencing the ubiquitination and proteasomal degradation of various substrates. By utilizing USP50 knockout cell lines, scientists can dissect the complex interaction networks of ubiquitination, thereby unveiling the impact of USP50 dysregulation in various conditions, such as cancer and neurodegenerative diseases. These cell lines act as a vital mechanism for understanding gene function, providing insights essential for both basic and applied biomedical research.

The scientific importance of USP50 Gene Knockout Cell Lines is underscored by their versatility in various applications, including drug discovery, biomarker validation, and functional genomics. Their utility in identifying potential therapeutic targets offers researchers a pathway toward developing innovative treatment strategies in clinical settings.

One of the key advantages of USP50 Gene Knockout Cell Lines compared to traditional cell models is their precision and reliability. The targeted knockout minimizes off-target effects, ensuring that experimental results remain valid and reproducible. Additionally, these lines are ready to use, significantly reducing preparation time and allowing researchers to focus on their scientific inquiries.

Researchers and clinicians alike will find valuable insights from these cell lines, enhancing their understanding of complex biological processes and aiding in the development of therapeutics. Our company, with its rich expertise in genetic engineering and commitment to quality, offers these USP50 Gene Knockout Cell Lines to empower the scientific community in their quest for breakthroughs in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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