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URGCP Knockout Cell Lines

Gene: URGCP

Official Full Name: upregulator of cell proliferationprovided by HGNC

Gene Summary: URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12768 URGCP Knockout cell line (HeLa) Human URGCP 1:3~1:6 Negative Online Inquiry
KO12769 URGCP Knockout cell line (HCT 116) Human URGCP 1:2~1:4 Negative Online Inquiry
KO12770 URGCP Knockout cell line (HEK293) Human URGCP 1:3~1:6 Negative Online Inquiry
KO12771 URGCP Knockout cell line (A549) Human URGCP 1:3~1:4 Negative Online Inquiry

Background

URGCP Gene Knockout Cell Lines are specifically engineered cell lines that have had the URGCP (upregulated gene in cancer) gene disrupted through targeted gene editing techniques, such as CRISPR-Cas9. By knocking out the URGCP gene, these cell lines provide researchers with valuable models to study the role of URGCP in various cellular processes, including proliferation, apoptosis, and tumorigenesis. This precise alteration enables scientists to investigate the gene's function and its implications in cancer biology.

The primary mechanism of action for the URGCP Gene Knockout Cell Lines lies in their ability to mimic the loss-of-function phenotype observed in specific cancers. Researchers can utilize these cell lines to assess the effects of URGCP depletion on signaling pathways, drug responses, and overall cellular behavior. This makes them invaluable tools for identifying therapeutic targets and validating new anti-cancer strategies.

The scientific importance of URGCP Gene Knockout Cell Lines extends to both fundamental research and translational applications. In academic laboratories, they facilitate the exploration of URGCP's contributions to oncogenesis and cancer progression. In clinical settings, understanding these mechanisms can help inform targeted therapies, ultimately improving patient outcomes.

Compared to traditional cell lines that may not accurately reflect the deletion of specific genes, URGCP Gene Knockout Cell Lines offer enhanced specificity and reproducibility. This precision allows for more accurate modeling of disease states, leading to more reliable experimental results and faster advancements in cancer research.

Researchers and clinicians will find great value in URGCP Gene Knockout Cell Lines due to their unique ability to serve as robust platforms for understanding cancer biology and identifying new treatment approaches. This, coupled with our extensive expertise in developing cutting-edge biological products, positions our company as a leader in providing high-quality research tools that advance scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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