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UBXN7 Knockout Cell Lines

Gene: UBXN7

Official Full Name: UBX domain protein 7provided by HGNC

Gene Summary: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; ubiquitin binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in nucleoplasm. Part of VCP-NPL4-UFD1 AAA ATPase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28440 UBXN7 Knockout cell line (HeLa) Human UBXN7 1:3~1:6 Negative Online Inquiry
KO28441 UBXN7 Knockout cell line (HCT 116) Human UBXN7 1:2~1:4 Negative Online Inquiry
KO28442 UBXN7 Knockout cell line (HEK293) Human UBXN7 1:3~1:6 Negative Online Inquiry
KO28443 UBXN7 Knockout cell line (A549) Human UBXN7 1:3~1:4 Negative Online Inquiry

Background

UBXN7 Gene Knockout Cell Lines represent a powerful tool for the study of gene function and regulation. These engineered mammalian cell lines have had the UBXN7 gene precisely disrupted, enabling researchers to investigate the role of this ubiquitin-associated protein in various biological processes. The knockout of UBXN7 facilitates an in-depth exploration of its contribution to cellular pathways, including protein degradation, stress response, and cellular signaling, thereby providing insights into mechanisms underlying diseases associated with cellular regulation.

The key function of UBXN7 is its involvement in the ubiquitin-proteasome system, a crucial process for maintaining cellular homeostasis by regulating protein turnover. By disrupting the UBXN7 gene, researchers can elucidate how the absence of this protein influences gene expression, protein interactions, and the degradation of substrate proteins. This allows for better understanding of disorders such as cancer, neurodegeneration, and other pathologies where protein homeostasis is disrupted.

The scientific importance of UBXN7 Gene Knockout Cell Lines lies in their applications for basic and applied research. These cell lines are particularly valuable in drug discovery and development, where understanding the pathway dynamics influenced by UBXN7 can yield novel therapeutic targets. Additionally, they serve as a platform for further investigations into cellular stress responses and adaptive mechanisms.

In comparison to traditional methods of gene silencing, such as RNA interference, the knockout approach offers a permanent and stable alteration of gene function, allowing for a more profound investigation of long-term cellular effects. This durability ensures that experimental results are reproducible and reliable, making these cell lines a superior option for researchers in molecular biology and genetics.

The UBXN7 Gene Knockout Cell Lines provide unparalleled value to researchers, clinicians, and pharmaceutical scientists seeking to understand complex cellular processes or develop innovative therapies. By utilizing these cell lines, users gain a reliable resource that facilitates high-impact research and the potential for significant advancements in clinical outcomes.

With a commitment to advancing biological research, our company specializes in providing well-characterized cell lines and molecular tools. Our expertise in cell line generation and maintenance ensures that researchers receive high-quality products that are essential for cutting-edge scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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