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UBXN4 Knockout Cell Lines

Gene: UBXN4

Official Full Name: UBX domain protein 4provided by HGNC

Gene Summary: UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP; MIM 601023) and promotes ER-associated protein degradation (ERAD) (Liang et al., 2006 [PubMed 16968747]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29722 UBXN4 Knockout cell line (HeLa) Human UBXN4 1:3~1:6 Negative Online Inquiry
KO29723 UBXN4 Knockout cell line (HCT 116) Human UBXN4 1:2~1:4 Negative Online Inquiry
KO29724 UBXN4 Knockout cell line (HEK293) Human UBXN4 1:3~1:6 Negative Online Inquiry
KO29725 UBXN4 Knockout cell line (A549) Human UBXN4 1:3~1:4 Negative Online Inquiry

Background

UBXN4 Gene Knockout Cell Lines are specially engineered cellular systems designed to provide a robust platform for the study of UBXN4 gene function. This product utilizes CRISPR/Cas9 technology to create precise knockouts of the UBXN4 gene, enabling researchers to investigate its role in various cellular processes and disease mechanisms. The knockout models facilitate the examination of gene function by providing a controlled environment where the effects of gene loss can be directly assessed.

These cell lines exhibit several key functions through their ability to modulate protein interactions and cellular responses. The UBXN4 gene is known to be involved in essential biological pathways, such as protein degradation and stress responses, making these knockout lines particularly valuable for dissecting the functional elements of these processes. By eliminating UBXN4, researchers can analyze alterations in cell signaling, proliferation, and tissue responsiveness, paving the way for insights into conditions like cancer and neurodegenerative diseases.

The scientific importance of UBXN4 Gene Knockout Cell Lines lies not only in their application in basic research but also in clinical settings. They are instrumental in drug discovery, target validation, and biomarker identification. Researchers can utilize these models to assess the ramifications of UBXN4 loss on therapeutic outcomes, providing a clearer context for the design of novel interventions.

In comparison to traditional knockout methods or overexpression systems, our UBXN4 Gene Knockout Cell Lines offer enhanced specificity and efficiency, with a significantly reduced off-target effect profile. This specificity ensures that researchers can attain accurate and reliable results, thereby increasing the reproducibility of experiments.

The value of these cell lines extends beyond the immediate research implications; they represent a strategic investment for researchers and clinicians aiming to understand complex disease mechanisms. The versatility of these models facilitates their integration into various experimental frameworks, thus enabling innovative approaches to therapeutic discovery and development.

With a strong foundation in molecular biology and a commitment to supporting the research community, our company specializes in providing high-quality biological tools designed to accelerate discovery and foster deeper understanding in the life sciences. Our expertise ensures that UBXN4 Gene Knockout Cell Lines are consistently validated and supported by robust technical resources, empowering scientists to advance their research effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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