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UBXN2A Knockout Cell Lines

Gene: UBXN2A

Official Full Name: UBX domain protein 2Aprovided by HGNC

Gene Summary: Predicted to enable ubiquitin binding activity. Involved in negative regulation of ERAD pathway and positive regulation of protein catabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12839 UBXN2A Knockout cell line (HeLa) Human UBXN2A 1:3~1:6 Negative Online Inquiry
KO12840 UBXN2A Knockout cell line (HCT 116) Human UBXN2A 1:2~1:4 Negative Online Inquiry
KO12841 UBXN2A Knockout cell line (HEK293) Human UBXN2A 1:3~1:6 Negative Online Inquiry
KO12842 UBXN2A Knockout cell line (A549) Human UBXN2A 1:3~1:4 Negative Online Inquiry

Background

UBXN2A Gene Knockout Cell Lines are an essential biological tool designed for the exploration and elucidation of the UBXN2A gene's role in cellular processes. These cell lines have been meticulously engineered to disrupt the UBXN2A gene, allowing researchers to investigate the consequences of its absence on various cellular functions, particularly in pathways related to protein homeostasis and stress responses. The knockout mechanism is facilitated through CRISPR/Cas9 technology, ensuring precise alteration of the gene sequence and enabling direct observation of the resultant phenotypic variations.

The primary functions of the UBXN2A gene knockout cell lines include examining the changes in ubiquitin signaling pathways, which are vital for protein degradation, and understanding how its absence affects cellular responses to stressors such as oxidative stress and proteasomal inhibition. This functionality offers researchers comprehensive insights into cellular mechanisms and their implications in diseases like cancer, neurodegeneration, and autoimmune disorders.

In scientific research and clinical settings, these knockout cell lines are invaluable for investigating the biological significance of UBXN2A, leading to translational applications. They allow researchers to model specific disease states, screen new therapeutic compounds, and develop targeted interventions that hinge on the modulation of related pathways.

The unique advantage of our UBXN2A Gene Knockout Cell Lines lies in their high specificity and reliability compared to other models. Unlike transient knockdown systems, these stable cell lines guarantee consistent experiments over time, reducing variability and enhancing reproducibility. This feature is critical when conducting long-term studies or those requiring precise gene editing to ensure valid conclusions.

For researchers and clinicians, the value of these knockout cell lines cannot be overstated; they represent a significant advancement in the ability to understand and manipulate cellular pathways associated with myriad diseases. Our company's commitment to quality and innovation in biological products, backed by a team of experienced scientists, ensures that you receive a product that meets the highest standards of research integrity. By choosing our UBXN2A Gene Knockout Cell Lines, you are equipping your research with a powerful tool for scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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