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UAP1 Knockout Cell Lines

Gene: UAP1

Official Full Name: UDP-N-acetylglucosamine pyrophosphorylase 1provided by HGNC

Gene Summary: Enables identical protein binding activity and protein serine pyrophosphorylase activity. Involved in antiviral innate immune response and positive regulation of type I interferon production. Located in nucleoplasm and plasma membrane. Is active in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35284 UAP1 Knockout cell line (HeLa) Human UAP1 1:3~1:6 Negative Online Inquiry
KO35285 UAP1 Knockout cell line (HCT 116) Human UAP1 1:2~1:4 Negative Online Inquiry
KO35286 UAP1 Knockout cell line (HEK293) Human UAP1 1:3~1:6 Negative Online Inquiry
KO35287 UAP1 Knockout cell line (A549) Human UAP1 1:3~1:4 Negative Online Inquiry

Background

UAP1 Gene Knockout Cell Lines are specially engineered cell lines designed to facilitate in-depth studies of the UAP1 gene's function and its role in various biological processes. These knockout cell lines have undergone targeted gene disruption, enabling researchers to observe the consequences of UAP1 gene deletion in cellular pathways. The unique mechanism of these cell lines operates through CRISPR-Cas9 genome editing technology, which not only ensures a precise knockout of the UAP1 gene but also minimizes off-target effects, thereby enhancing the integrity of experimental results.

The scientific importance of UAP1 Gene Knockout Cell Lines cannot be overstated; they serve as critical tools in unraveling the complexities of metabolic pathways, disease mechanisms, and potential therapeutic targets. In various research settings, these cell lines are instrumental in studying the biosynthetic pathways of glycoproteins and their effects in cellular homeostasis and signal transduction. Clinically, insights gained from using these knockout models can lead to the identification of novel biomarkers and therapeutic strategies for diseases influenced by UAP1 functions, such as cancer, neurodegenerative diseases, and metabolic disorders.

One of the primary advantages of UAP1 Gene Knockout Cell Lines is the specificity of the genetic alteration, allowing researchers to generate reproducible and reliable data. Unlike other methods that may lead to partial knockouts or unintended genetic changes, our cell lines provide a clean genetic background that maximizes experimental accuracy. Additionally, our UAP1 knockout lines are readily available with characterized phenotypes, saving valuable time for researchers requiring immediate access to these models.

For researchers and clinicians seeking to advance their studies, UAP1 Gene Knockout Cell Lines represent a valuable asset, enabling the exploration of UAP1’s biochemical roles with unprecedented clarity. By choosing our product, users can leverage cutting-edge technology backed by extensive expertise in genetic engineering and cell line development, ensuring a high-quality research foundation that aligns with their scientific goals.

Please note that all services are for research use only. Not intended for any clinical use.

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