Gene: TYRO3
Official Full Name: TYRO3 protein tyrosine kinaseprovided by HGNC
Gene Summary: The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09881 | TYRO3 Knockout cell line (HeLa) | Human | TYRO3 | 1:3~1:6 | Negative | Online Inquiry |
KO09882 | TYRO3 Knockout cell line (HCT 116) | Human | TYRO3 | 1:2~1:4 | Negative | Online Inquiry |
KO09883 | TYRO3 Knockout cell line (HEK293) | Human | TYRO3 | 1:3~1:6 | Negative | Online Inquiry |
KO09884 | TYRO3 Knockout cell line (A549) | Human | TYRO3 | 1:3~1:4 | Negative | Online Inquiry |
TYRO3 Gene Knockout Cell Lines are highly specialized cellular models designed to study the role of the TYRO3 gene, a member of the TAM receptor family, in various biological processes and diseases. Gene knockout technology involves the targeted disruption of a specific gene, leading to a complete loss of its function. This innovative product provides researchers with valuable tools to investigate the effects of TYRO3 depletion on cellular signaling pathways, immune responses, and tumor biology.
The primary mechanism through which these cell lines function involves the deletion of the TYRO3 gene, resulting in altered cellular behaviors and responses. This can reveal insights into the gene's involvement in critical functions such as cell proliferation, migration, and apoptosis. Moreover, these knockout models can contribute to understanding terminal cell fate decisions and the modulation of immune cell activity during pathological states, including cancer and autoimmune diseases.
The scientific importance of TYRO3 Gene Knockout Cell Lines is underscored by their applications in both basic research and translational medicine. Researchers can utilize these cell lines to explore therapeutic interventions targeting TYRO3, potentially leading to novel treatment strategies for various conditions. Furthermore, the insights gained from using these models can enhance our understanding of receptor tyrosine kinases in health and disease.
Compared to alternative products, these cell lines offer unique advantages such as high specificity, reproducibility, and consistency, ensuring reliable data generation during experimental procedures. Researchers will value the precise characterization of cellular responses in the absence of TYRO3 while recognizing the ethical implications of utilizing in vitro models that reduce the need for animal studies.
The value of TYRO3 Gene Knockout Cell Lines lies in their unparalleled capacity to advance our understanding of gene function and its implications in disease, thereby serving as a critical asset for researchers and clinicians focused on innovative treatment approaches. Our company prides itself on its deep expertise in genetic engineering and cell line development, ensuring our products meet the highest standards of quality and efficacy for the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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