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TXNDC15 Knockout Cell Lines

Gene: TXNDC15

Official Full Name: thioredoxin domain containing 15provided by HGNC

Gene Summary: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. [provided by RefSeq, Apr 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12914 TXNDC15 Knockout cell line (HeLa) Human TXNDC15 1:3~1:6 Negative Online Inquiry
KO12915 TXNDC15 Knockout cell line (HCT 116) Human TXNDC15 1:2~1:4 Negative Online Inquiry
KO12916 TXNDC15 Knockout cell line (HEK293) Human TXNDC15 1:3~1:6 Negative Online Inquiry
KO12917 TXNDC15 Knockout cell line (A549) Human TXNDC15 1:3~1:4 Negative Online Inquiry

Background

TXNDC15 Gene Knockout Cell Lines are a specialized biological product designed to facilitate the study of the TXNDC15 gene's function by creating a definitive model of loss of function. These cell lines are generated using advanced gene editing technologies, such as CRISPR-Cas9, to precisely disrupt the TXNDC15 gene, an essential player in cellular redox homeostasis and protein folding processes within the endoplasmic reticulum. By providing researchers with a systematized approach to study the consequences of TXNDC15 deletion, these cell lines enable the exploration of various biological pathways influenced by oxidative stress and protein misfolding diseases.

At the heart of their functionality, these knockout cell lines allow for the investigation of mechanistic pathways involved in cellular responses to stress, apoptosis, and disease. Researchers can utilize these models to elucidate the role of TXNDC15 in conditions such as neurodegeneration, cancer, and metabolic disorders. The ability to compare these knockout lines against wild-type controls provides insights into the specific contributions of TXNDC15 in cellular physiology and pathology.

The scientific importance of TXNDC15 Gene Knockout Cell Lines extends to both fundamental and applied research settings. They serve as valuable tools for drug discovery and testing, allowing scientists to screen compounds that may counteract the effects of TXNDC15 loss. Additionally, these lines can be employed in the development of gene therapies targeting TXNDC15-related diseases.

What sets TXNDC15 Gene Knockout Cell Lines apart from alternatives, such as knockdown models or non-specific genetic alterations, is their complete and stable gene deletion. This ensures a robust platform for reproducibility in experimental results, minimizing variability that can arise from incomplete gene silencing. Furthermore, the lines can be readily adapted to various cellular assays, such as cell viability, proliferation, and signaling studies.

For researchers, clinicians, and biotechnology companies, the TXNDC15 Gene Knockout Cell Lines represent an invaluable resource that accelerates translational research and enhances understanding of TXNDC15's biological role. Investing in these cell lines empowers scientific exploration and innovation, paving the way for therapeutic advancements.

As a leader in the field of genetic engineering and biological products, our company prides itself on providing high-quality, validated cell lines tailored to meet the needs of the research community. We are committed to supporting your scientific endeavors with our expertise and comprehensive product offerings.

Please note that all services are for research use only. Not intended for any clinical use.

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