Gene: TUFT1
Official Full Name: tuftelin 1provided by HGNC
Gene Summary: Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation. [provided by RefSeq, Aug 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34886 | TUFT1 Knockout cell line (HeLa) | Human | TUFT1 | 1:3~1:6 | Negative | Online Inquiry |
KO34887 | TUFT1 Knockout cell line (HCT 116) | Human | TUFT1 | 1:2~1:4 | Negative | Online Inquiry |
KO34888 | TUFT1 Knockout cell line (HEK293) | Human | TUFT1 | 1:3~1:6 | Negative | Online Inquiry |
KO34889 | TUFT1 Knockout cell line (A549) | Human | TUFT1 | 1:3~1:4 | Negative | Online Inquiry |
TUFT1 Gene Knockout Cell Lines are specifically engineered cellular models in which the TUFT1 gene has been selectively disrupted, allowing researchers to investigate the biological role of this gene in a controlled environment. These knockout cell lines provide a unique platform for examining tumor biology, cellular signaling pathways, and gene functions associated with various diseases, particularly in cancer research.
The primary function of TUFT1 Gene Knockout Cell Lines is to eliminate the expression of the TUFT1 gene, which encodes a protein associated with oncogenic processes and cellular proliferation. Utilizing CRISPR-Cas9 technology, these cell lines enable precise gene editing, resulting in effective disruption of TUFT1 expression. By comparing these knockout cells with their wild-type counterparts, researchers can gain insights into how the absence of TUFT1 impacts cellular behavior, gene expression profiles, and overall metabolic pathways.
From a scientific perspective, these cell lines are invaluable for elucidating the TUFT1 gene's role in cellular mechanisms and its potential as a therapeutic target. They are applicable in various research settings, including drug response experiments and the study of tumor microenvironments, making them essential tools for both academic and pharmaceutical research.
The advantage of TUFT1 Gene Knockout Cell Lines lies in their specificity and versatility. Unlike traditional genetic manipulation methods, the CRISPR-Cas9 approach enables more reliable and reproducible gene disruption. Moreover, these cell lines are ready-to-use, saving researchers time on preliminary experiments and enhancing their productivity. This streamlined approach positions TUFT1 gene knockout models as a superior option compared to earlier methods of gene silencing.
For researchers and clinicians focused on understanding cancer biology and developing targeted therapies, TUFT1 Gene Knockout Cell Lines offer a compelling opportunity to advance their work. Their potential to transform insights into actionable data makes them a wise investment in the landscape of genetic research.
Our company has a proven track record in providing high-quality, biologically relevant products tailored for cutting-edge research. With robust expertise in cell line development and gene editing technologies, we ensure that our customers receive top-tier resources to advance their scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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