Gene: TUBG2
Official Full Name: tubulin gamma 2provided by HGNC
Gene Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic sister chromatid segregation. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27761 | TUBG2 Knockout cell line (HeLa) | Human | TUBG2 | 1:3~1:6 | Negative | Online Inquiry |
KO27762 | TUBG2 Knockout cell line (HCT 116) | Human | TUBG2 | 1:2~1:4 | Negative | Online Inquiry |
KO27763 | TUBG2 Knockout cell line (HEK293) | Human | TUBG2 | 1:3~1:6 | Negative | Online Inquiry |
KO27764 | TUBG2 Knockout cell line (A549) | Human | TUBG2 | 1:3~1:4 | Negative | Online Inquiry |
TUBG2 Gene Knockout Cell Lines are genetically engineered cell lines in which the TUBG2 gene, a crucial component of the microtubule organizing center, has been inactivated or eliminated. This specific gene plays an essential role in microtubule stability and organization during cell division, making these knockout cell lines invaluable for studying the genetic contributions to cellular architecture, mitotic processes, and functional manipulation of cellular pathways.
The primary mechanism through which TUBG2 gene knockout operates involves the disruption of the gene’s coding sequence, leading to the absence of TUBG2 protein. This results in significant alterations in microtubule dynamics, impacting various cellular functions such as cytokinesis, intracellular transport, and signal transduction. Researchers utilize these cell lines to uncover the roles of TUBG2 in health and disease, including cancer, neurodegenerative disorders, and cellular response to environmental stress.
In both research and clinical settings, TUBG2 Gene Knockout Cell Lines are of scientific importance for providing insights into cytoskeletal organization and its implications in cell-cycle regulation and tumorigenesis. Their utility spans diverse applications, from drug screening and target validation to the development of novel therapeutic strategies aimed at restoring normal microtubule function in diseased cells.
One of the unique advantages of TUBG2 Gene Knockout Cell Lines is their specificity and reliability in deconstructing the molecular mechanisms underlying microtubule-related pathologies. Unlike conventional pharmacological interventions, these models allow for precise genetic dissection, enabling a more profound understanding of the biology involved, with less risk of off-target effects.
By incorporating TUBG2 knockout models into experimental designs, researchers can enhance the reproducibility and accuracy of their findings, accelerating the journey from basic research to potential therapeutic developments. Investing in our TUBG2 Gene Knockout Cell Lines signifies a commitment to employing cutting-edge genetic tools to foster impactful scientific discovery.
Our company maintains a strong legacy in generating high-quality, genetically modified cell lines, backed by rigorous validation protocols and a dedication to supporting the evolving needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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