Gene: TUBB6
Official Full Name: tubulin beta 6 class Vprovided by HGNC
Gene Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in intercellular bridge; microtubule; and mitotic spindle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24773 | TUBB6 Knockout cell line (HeLa) | Human | TUBB6 | 1:3~1:6 | Negative | Online Inquiry |
KO24774 | TUBB6 Knockout cell line (HCT 116) | Human | TUBB6 | 1:2~1:4 | Negative | Online Inquiry |
KO24775 | TUBB6 Knockout cell line (HEK293) | Human | TUBB6 | 1:3~1:6 | Negative | Online Inquiry |
KO24776 | TUBB6 Knockout cell line (A549) | Human | TUBB6 | 1:3~1:4 | Negative | Online Inquiry |
TUBB6 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the TUBB6 gene, which plays a critical role in microtubule dynamics and cellular function. These knockout cell lines allow researchers to investigate the specific biological processes governed by the TUBB6 gene, including cell division, neuronal development, and various signaling pathways. By eliminating this gene’s contribution, scientists can discern its role in pathology, drug responses, and cellular behavior, thereby advancing the understanding of a multitude of biological systems.
The mechanism underpinning TUBB6 gene knockout involves targeted gene editing techniques, often utilizing CRISPR/Cas9 technology, which ensures precise disruption of the gene, leading to a loss of function. This specific approach permits a comprehensive analysis of how the absence of TUBB6 influences microtubule stability and cellular morphology, providing insights into the broader implications for cellular health and pathology associated with its dysfunction.
The scientific importance of TUBB6 gene knockout cell lines lies in their application in both research and clinical contexts. These cell lines can serve as valuable tools for screening potential therapeutic interventions, studying neurodegenerative diseases, and exploring the mechanisms of cancer progression, where misregulation of microtubule dynamics is often evident.
What sets TUBB6 gene knockout cell lines apart from alternative models is their unique targeting of a key regulatory element within microtubule formation without the confounding effects of off-target genetic alterations. This ensures high fidelity in experimental results, making the data derived from these models more robust and reliable.
For researchers and clinicians, investing in TUBB6 gene knockout cell lines translates to access to a highly relevant and functionally informative model system that can accelerate discoveries across numerous biological fields. Our expertise in developing and producing high-quality cell lines ensures that you receive products tailored for reproducibility and consistency in your experiments, thereby empowering your research endeavors with unparalleled precision and efficacy.
Please note that all services are for research use only. Not intended for any clinical use.
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