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TUBA1C Knockout Cell Lines

Gene: TUBA1C

Official Full Name: tubulin alpha 1cprovided by HGNC

Gene Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in microtubule cytoskeleton and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24637 TUBA1C Knockout cell line (HeLa) Human TUBA1C 1:3~1:6 Negative Online Inquiry
KO24638 TUBA1C Knockout cell line (HCT 116) Human TUBA1C 1:2~1:4 Negative Online Inquiry
KO24639 TUBA1C Knockout cell line (HEK293) Human TUBA1C 1:3~1:6 Negative Online Inquiry
KO24640 TUBA1C Knockout cell line (A549) Human TUBA1C 1:3~1:4 Negative Online Inquiry

Background

TUBA1C Gene Knockout Cell Lines are genetically modified cell lines in which the TUBA1C gene, encoding the protein tubulin alpha-1C, has been selectively disrupted. This gene plays a crucial role in microtubule formation and intracellular transport, key processes for maintaining cellular structure and function. The knockout of the TUBA1C gene enables researchers to investigate the impact of microtubule dynamics on various cellular processes, providing valuable insights into cellular mechanics and signaling pathways.

These knockout cell lines utilize state-of-the-art CRISPR/Cas9 gene editing technology to achieve high specificity and efficiency in gene disruption. By removing the TUBA1C genetic sequence, researchers can assess the resultant phenotypic changes, including alterations in cell morphology, proliferation rates, and response to treatment. This makes the TUBA1C gene knockout an essential tool for studying diseases linked to cytoskeletal abnormalities, such as cancer and neurodegenerative disorders.

The scientific importance of TUBA1C Gene Knockout Cell Lines extends to both fundamental research and clinical applications. They offer a unique system for modeling diseases, understanding microtubule-related disorders, and screening potential therapeutics that target microtubule dynamics. Moreover, as the TUBA1C gene is implicated in various pathophysiological conditions, exploring its functional relevance can lead to novel drug discovery avenues.

Compared to alternatives, such as transient knockdown techniques or traditional knockout models, TUBA1C Gene Knockout Cell Lines present a stable and reproducible system for long-term studies with minimal background noise, enhancing experimental reliability. Their robustness allows researchers to achieve consistent results over time, which is crucial for validating hypotheses in cellular biology.

For researchers and clinicians seeking reliable and innovative models for genetic and cellular studies, TUBA1C Gene Knockout Cell Lines are indispensable resources that facilitate the exploration of critical biological questions. With a commitment to quality and scientific advancement, our company provides these advanced cell lines backed by extensive expertise in genetic engineering and cellular biology, supporting the global research community in uncovering the mechanisms of life.

Please note that all services are for research use only. Not intended for any clinical use.

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