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TSSK6 Knockout Cell Lines

Gene: TSSK6

Official Full Name: testis specific serine kinase 6provided by HGNC

Gene Summary: This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25284 TSSK6 Knockout cell line (HCT 116) Human TSSK6 1:2~1:4 Negative Online Inquiry
KO25285 TSSK6 Knockout cell line (A549) Human TSSK6 1:3~1:4 Negative Online Inquiry

Background

TSSK6 Gene Knockout Cell Lines are advanced cellular models specifically designed to investigate the functional role of the TSSK6 gene in various biological processes. TSSK6, or Testis-Specific Serine Kinase 6, is implicated in spermatogenesis and fertility, making these knockout cell lines crucial for studying reproductive biology and associated disorders. By utilizing CRISPR/Cas9 technology, these cell lines possess a precisely edited genome that completely abrogates TSSK6 expression, allowing researchers to discern its physiological roles and regulatory mechanisms without the interference of the wild-type gene.

The key function of TSSK6 Gene Knockout Cell Lines lies in their ability to facilitate the understanding of gene function in cellular contexts. The absence of TSSK6 uncovers novel insights into spermatogenic pathways, potentially unveiling therapeutic targets for male infertility. Mechanistically, these knockout lines permit the assessment of downstream signaling cascades affected by TSSK6, as well as the examination of alterations in cell morphology, proliferation, and differentiation, vital for understanding the broader implications in reproductive health.

The scientific importance of these knockout cell lines is paramount in both research and clinical settings. They serve as invaluable tools for drug development and testing strategies against male infertility, advancing the frontline of reproductive health solutions. Moreover, researchers can leverage these models to explore the interaction of TSSK6 with other signaling pathways, enhancing the understanding of related molecular biology.

What sets TSSK6 Gene Knockout Cell Lines apart from alternative models is their specificity and precision, which allow for a focused investigation of TSSK6 in a controlled environment. Many traditional knockout models may not fully eliminate gene expression or may introduce compensatory mechanisms, skewing results. Our product provides unambiguous, validated data essential for groundbreaking findings.

For researchers and clinicians, the TSSK6 Gene Knockout Cell Lines open avenues for groundbreaking discoveries in reproductive biology, providing a reliable and efficient means to dissect gene function. By integrating these innovative cell lines into research programs, users can expect enhanced reproducibility and accuracy in experimental outcomes.

Our company, dedicated to pioneering biological research solutions, is committed to offering products that empower scientists to make novel discoveries. We bring expertise and innovation to the forefront of molecular biology and reproductive health research, ensuring our customers have access to top-tier cellular models.

Please note that all services are for research use only. Not intended for any clinical use.

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