Gene: TSN
Official Full Name: translinprovided by HGNC
Gene Summary: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06141 | TSN Knockout cell line (HeLa) | Human | TSN | 1:3~1:6 | Negative | Online Inquiry |
KO06142 | TSN Knockout cell line (HCT 116) | Human | TSN | 1:2~1:4 | Negative | Online Inquiry |
KO06143 | TSN Knockout cell line (HEK293) | Human | TSN | 1:3~1:6 | Negative | Online Inquiry |
KO06144 | TSN Knockout cell line (A549) | Human | TSN | 1:3~1:4 | Negative | Online Inquiry |
TSN Gene Knockout Cell Lines are specialized cultured cell lines that have undergone precise genetic alteration to disrupt the expression of the TSN gene. This innovative product offers researchers a highly valuable tool for investigating the role of TSN in various biological processes, including cell growth, differentiation, and response to stress. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines allow for a consistent and reproducible approach to studying the functions of TSN in cellular models.
The primary function of TSN Gene Knockout Cell Lines lies in their ability to create a controlled environment where the influence of TSN can be thoroughly examined. The knockout mechanism enables researchers to observe resultant phenotypic changes and cellular signaling pathways that are activated or repressed in the absence of TSN. This can lead to a deeper understanding of fundamental biological processes and potential disease mechanisms.
In scientific and clinical research settings, these knockout cell lines are critical for advancing knowledge in areas such as cancer biology, developmental biology, and gene therapy. They can be essential for testing therapeutic compounds or evaluating the efficacy of drugs targeting TSN-related pathways. Moreover, they have the potential to serve as robust models for studying gene function and elucidating the pathophysiology of various diseases linked to TSN dysregulation.
What sets our TSN Gene Knockout Cell Lines apart from alternative products is their high fidelity and ease of use. Each cell line is extensively validated, ensuring that researchers receive reliable data, which is particularly crucial for high-stakes projects such as drug development. Furthermore, these cell lines come with comprehensive support and documentation, enhancing user experience and streamlining experimental workflows.
Utilizing TSN Gene Knockout Cell Lines not only accelerates the pace of research but also holds significant promise for translational applications in medicine. These cell lines provide a pathway to uncover novel therapeutic targets and strategies, making them indispensable for both academic and clinical researchers.
Our company specializes in providing high-quality biological products backed by rigorous scientific research and expertise. With a commitment to excellence and innovation, we aim to equip researchers with the tools they need to push the boundaries of knowledge in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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