Gene: TRIM38
Official Full Name: tripartite motif containing 38provided by HGNC
Gene Summary: This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31797 | TRIM38 Knockout cell line (HeLa) | Human | TRIM38 | 1:3~1:6 | Negative | Online Inquiry |
KO31798 | TRIM38 Knockout cell line (HCT 116) | Human | TRIM38 | 1:2~1:4 | Negative | Online Inquiry |
KO31799 | TRIM38 Knockout cell line (HEK293) | Human | TRIM38 | 1:3~1:6 | Negative | Online Inquiry |
KO31800 | TRIM38 Knockout cell line (A549) | Human | TRIM38 | 1:3~1:4 | Negative | Online Inquiry |
TRIM38 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study and functional characterization of the TRIM38 gene, a member of the tripartite motif (TRIM) protein family involved in various cellular processes, including immune response regulation and tumorigenesis. These knockout cell lines are created through advanced CRISPR-Cas9 gene-editing technology, ensuring a precise removal of the TRIM38 gene to enable researchers to analyze its biological functions in a controlled environment.
The primary mechanism of action for TRIM38 involves modulating signaling pathways relevant to immune responses and cellular proliferation. By knocking out this gene, researchers can investigate the subsequent effects on these pathways, enabling a deeper understanding of how TRIM38 influences disease mechanisms such as cancer, autoimmune disorders, and viral infection responses. This is particularly valuable in translational research, where insights gained can lead to novel therapeutic targets.
In comparison to traditional methods, such as RNA interference, TRIM38 Gene Knockout Cell Lines provide a more stable and permanent alteration of gene expression, eliminating variable knockdown effects over time. This advantage makes them an essential tool for reproducible and reliable research outcomes.
The scientific importance of these knockout cell lines is underscored by their applicability in drug discovery, functional genomics, and the development of personalized medicine strategies. For researchers and clinicians focused on dissecting the complexities of immune responses or cancer biology, these cell lines offer a unique opportunity to advance their work.
With a commitment to scientific excellence, our company specializes in providing high-quality genetic models, including the TRIM38 Gene Knockout Cell Lines. Our expertise in genetic engineering equips researchers with the best tools available for cutting-edge biological research and innovative clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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