Gene: TRAM1L1
Official Full Name: translocation associated membrane protein 1 like 1provided by HGNC
Gene Summary: Predicted to be involved in protein insertion into ER membrane. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26497 | TRAM1L1 Knockout cell line (HeLa) | Human | TRAM1L1 | 1:3~1:6 | Negative | Online Inquiry |
KO26498 | TRAM1L1 Knockout cell line (A549) | Human | TRAM1L1 | 1:3~1:4 | Negative | Online Inquiry |
TRAM1L1 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to study the effects of TRAM1L1 gene disruption on cellular behaviors and pathways. The TRAM1L1 gene encodes a transmembrane protein involved in cellular processes such as autophagy, immune responses, and vesicular trafficking. By creating knockout models through CRISPR-Cas9 technology, researchers can effectively investigate the physiological roles and implications of TRAM1L1 in various biological systems.
These cell lines function by enabling the precise deletion or mutation of the TRAM1L1 gene. As a result, researchers can observe downstream effects on cellular signaling pathways and examine phenotypic changes that occur in response to the absence of this specific protein. Understanding these mechanisms is crucial in elucidating the gene's role in cellular stress responses, potential disease mechanisms, and therapeutic targets, which holds significant promise in both translational and fundamental research.
The scientific importance of TRAM1L1 Gene Knockout Cell Lines lies in their applicability across multiple domains. They can provide valuable insights for researchers studying neurodegenerative diseases, cancer biology, and immune dysfunctions. In clinical settings, delineating the role of TRAM1L1 may pave the way for innovative therapeutic strategies targeting these pathways.
Compared to conventional wild-type cell lines, these knockout cell lines present distinct advantages, including enhanced specificity in experimental setups and the ability to detect subtle biological changes that may otherwise be masked in non-modified cells. Researchers and clinicians seeking to deepen their understanding of TRAM1L1-related pathways will find these models invaluable, driving advancements in gene editing technologies and their applications.
In conclusion, our company, with its commitment to providing high-quality biological products and cutting-edge genetic tools, offers robust TRAM1L1 Gene Knockout Cell Lines that support innovative research endeavors, enabling scientists to explore the functional landscape of TRAM1L1 and its broader implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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