Gene: TRAM1
Official Full Name: translocation associated membrane protein 1provided by HGNC
Gene Summary: This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05957 | TRAM1 Knockout cell line (HeLa) | Human | TRAM1 | 1:3~1:6 | Negative | Online Inquiry |
KO05958 | TRAM1 Knockout cell line (HCT 116) | Human | TRAM1 | 1:2~1:4 | Negative | Online Inquiry |
KO05959 | TRAM1 Knockout cell line (HEK293) | Human | TRAM1 | 1:3~1:6 | Negative | Online Inquiry |
KO05960 | TRAM1 Knockout cell line (A549) | Human | TRAM1 | 1:3~1:4 | Negative | Online Inquiry |
TRAM1 Gene Knockout Cell Lines are advanced cellular models engineered to lack the expression of the TRAM1 gene, a crucial component involved in protein transport and cellular signaling pathways. This product is essential for investigating the role of TRAM1 in various biological processes, including immunomodulation, cell differentiation, and intracellular trafficking. The knockout mechanism is achieved through cutting-edge gene editing technologies, such as CRISPR/Cas9, which ensures precise and efficient disruption of the TRAM1 gene, enabling researchers to study its functional consequences at both molecular and cellular levels.
The primary function of these knockout cell lines is to elucidate the biological roles of TRAM1 in health and disease. By examining how the absence of TRAM1 affects cellular behavior, researchers can gain insights into its involvement in pathophysiological conditions, such as cancer and autoimmune diseases. The TRAM1 Gene Knockout Cell Lines serve as valuable tools in pharmacological studies, enabling scientists to screen potential therapeutic agents and assess their efficacy against TRAM1-related mechanisms.
What sets our TRAM1 Gene Knockout Cell Lines apart from alternatives is their rigorous validation process, ensuring that the gene knockout is both complete and phenotypically stable across passages. These cell lines are backed by extensive characterization data, providing confidence in their utility for experimental applications. Additionally, they are compatible with a variety of assay formats, including high-throughput screening, making them versatile tools for researchers.
For scientists, the value of using TRAM1 Gene Knockout Cell Lines lies in their ability to facilitate deeper understanding of complex biological mechanisms and inform future therapeutic strategies. Clinicians can also leverage these models to explore novel biomarkers and develop targeted interventions based on genetic insights.
Our company prides itself on expertise in cell line development and genetic engineering, offering a robust portfolio of knockout and knock-in models. By choosing our TRAM1 Gene Knockout Cell Lines, you invest in a reliable resource that can drive your research forward with confidence and clarity.
Please note that all services are for research use only. Not intended for any clinical use.
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