Gene: TRA
Official Full Name: T cell receptor alpha locusprovided by HGNC
Gene Summary: Enables signaling receptor activity. Contributes to peptide antigen binding activity. Involved in T cell activation involved in immune response; T cell mediated cytotoxicity directed against tumor cell target; and detection of tumor cell. Located in cell surface. Part of alpha-beta T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35075 | TRA Knockout cell line (HeLa) | Human | TRA | 1:3~1:6 | Negative | Online Inquiry |
KO35076 | TRA Knockout cell line (HCT 116) | Human | TRA | 1:2~1:4 | Negative | Online Inquiry |
KO35077 | TRA Knockout cell line (HEK293) | Human | TRA | 1:3~1:6 | Negative | Online Inquiry |
KO35078 | TRA Knockout cell line (A549) | Human | TRA | 1:3~1:4 | Negative | Online Inquiry |
TRA Gene Knockout Cell Lines are specialized cell lines engineered to have specific genes disrupted or entirely removed, allowing for precise investigation into gene function and the biological pathways they influence. This innovative product harnesses the power of CRISPR/Cas9 technology, an advanced gene-editing technique that enables the targeted modification of genomic sequences. By knocking out TRA genes, researchers can effectively model conditions associated with gene dysfunction, making these cell lines invaluable tools for studying diseases, gene interactions, and the cellular impact of novel therapeutic approaches.
The key functions of TRA Gene Knockout Cell Lines involve the disruption of target gene expression, which elucidates the role of those genes in cellular processes such as proliferation, differentiation, apoptosis, and immune response. Researchers can employ these cell lines to further understand mechanisms underlying various diseases, including cancer, autoimmune disorders, and infectious diseases, creating opportunities for breakthrough discoveries in therapeutic interventions.
Scientifically, these cell lines are of paramount importance in both research and clinical settings. They facilitate high-throughput screening for drug candidates and contribute to the development of gene therapies by enabling a deeper understanding of genetic contributions to pathology. Researchers in academia and industry can leverage these models to validate targets for novel treatments, ensuring that their findings can bridge the gap between fundamental research and clinical application.
Compared to alternative models, such as traditional knockout mice or less specific cell lines, TRA Gene Knockout Cell Lines offer significant advantages: rapid generation times, cost-effectiveness, and the ability to manipulate a range of specific genes with high precision. This not only accelerates the research timeline but also enhances reproducibility and consistency across experiments.
The value of TRA Gene Knockout Cell Lines to researchers and clinicians lies in their ability to provide insights that drive innovation in areas such as drug development, gene therapy, and personalized medicine. With these tools, scientists can unravel complex biological questions and translate their findings into impactful clinical applications.
At [Your Company Name], we are committed to delivering cutting-edge biological research tools backed by extensive expertise in gene editing technologies. With our TRA Gene Knockout Cell Lines, we equip researchers with the means to explore the fundamental aspects of genetics, advancing science toward a healthier future.
Please note that all services are for research use only. Not intended for any clinical use.
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