Gene: TP53INP1
Official Full Name: tumor protein p53 inducible nuclear protein 1provided by HGNC
Gene Summary: Predicted to enable antioxidant activity. Involved in autophagic cell death; positive regulation of DNA-templated transcription; and positive regulation of autophagy. Located in autophagosome; cytosol; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22046 | TP53INP1 Knockout cell line (HeLa) | Human | TP53INP1 | 1:3~1:6 | Negative | Online Inquiry |
KO22047 | TP53INP1 Knockout cell line (HCT 116) | Human | TP53INP1 | 1:2~1:4 | Negative | Online Inquiry |
KO22048 | TP53INP1 Knockout cell line (HEK293) | Human | TP53INP1 | 1:3~1:6 | Negative | Online Inquiry |
KO22049 | TP53INP1 Knockout cell line (A549) | Human | TP53INP1 | 1:3~1:4 | Negative | Online Inquiry |
TP53INP1 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the tumor suppressor protein p53 and its associated pathways. TP53INP1 (Tumor Protein 53 Induced Nuclear Protein 1) plays a crucial role in cellular responses to stressors, such as DNA damage and hypoxia, and is integral to p53-mediated tumor suppression mechanisms. The creation of these knockout cell lines involves the targeted disruption of the TP53INP1 gene, leading to a loss of its function that enables researchers to investigate the protein's downstream effects and interactions more effectively.
These cell lines are valuable in understanding the mechanistic pathways through which p53 exerts its influence on cell cycle regulation, apoptosis, and responses to chemotherapy, thus shedding light on cancer biology and potential therapeutic strategies. By using TP53INP1 Gene Knockout Cell Lines, scientists can dissect the contribution of TP53INP1 in various stress responses, enabling the identification of novel biomarkers or therapeutic targets in cancer treatment.
The primary advantages of our TP53INP1 Gene Knockout Cell Lines include their robustness, validated genetic modification, and reproducibility in experimental protocols. Unlike traditional models, our cell lines provide a more precise mimicry of p53 dysfunction, thus enhancing the reliability of preclinical studies. Additionally, these lines offer a user-friendly experience, complementing existing genetic tools available in laboratories.
For researchers and clinicians seeking to deepen their understanding of tumor biology and refine their approaches to cancer treatment, the TP53INP1 Gene Knockout Cell Lines represent an essential addition to their research arsenal. With expertise in developing innovative biological products, our company is committed to supporting the scientific community in advancing cancer research and therapeutic development. We ensure that our products are of the highest quality, rigorously tested, and designed to meet the evolving needs of researchers in the field.
Please note that all services are for research use only. Not intended for any clinical use.
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