Gene: TOX4
Official Full Name: TOX high mobility group box family member 4provided by HGNC
Gene Summary: Predicted to enable chromatin DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in chromatin and chromosome, telomeric region. Part of PTW/PP1 phosphatase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32591 | TOX4 Knockout cell line (HeLa) | Human | TOX4 | 1:3~1:6 | Negative | Online Inquiry |
KO32592 | TOX4 Knockout cell line (HCT 116) | Human | TOX4 | 1:2~1:4 | Negative | Online Inquiry |
KO32593 | TOX4 Knockout cell line (HEK293) | Human | TOX4 | 1:3~1:6 | Negative | Online Inquiry |
KO32594 | TOX4 Knockout cell line (A549) | Human | TOX4 | 1:3~1:4 | Negative | Online Inquiry |
TOX4 Gene Knockout Cell Lines represent a specialized collection of genetically engineered cell lines where the TOX4 gene has been inactivated through targeted gene knockout techniques. This innovative product allows researchers to study the functional role of the TOX4 gene within various cellular contexts. It is particularly impactful in elucidating mechanisms tied to cellular stress responses, apoptosis, and other critical pathways linked to gene regulation and expression.
The key function of TOX4 Gene Knockout Cell Lines lies in their ability to model the loss of TOX4 gene function, enabling scientists to investigate how this alteration affects cellular behavior, signaling pathways, and gene interactions. By leveraging techniques such as CRISPR/Cas9 or RNA interference, the knockout of TOX4 provides a powerful platform for studying the gene's contributions to both normal physiology and disease states, particularly in cancer research and neurobiology.
The scientific importance of these cell lines cannot be overstated, as they offer vital insights into the pathophysiological roles played by TOX4, paving the way for potential therapeutic interventions. In clinical settings, understanding TOX4's role may lead to the identification of biomarkers for diseases where its dysregulation occurs, thereby enhancing diagnostic and prognostic capabilities.
When compared to alternative models, TOX4 Gene Knockout Cell Lines are uniquely valuable due to their precise gene editing, reliability in results, and ability to replicate human cellular responses. They serve as superior tools over traditional knockdown approaches or non-specific gene silencing methods, as knockout exhibits a complete loss of function, allowing for clearer observations of phenotypic changes.
For researchers, clinicians, and biopharmaceutical companies, incorporating TOX4 Gene Knockout Cell Lines into their experiments can streamline the understanding of gene functions and contribute to the development of innovative treatments. The movement towards targeted therapies and more personalized medicine makes these cell lines an indispensable resource.
Our company specializes in the development and provision of cutting-edge genetic models, ensuring high-quality and reliable biological products tailored to support the advancing fields of genetics, molecular biology, and translational research. With experience in state-of-the-art gene editing technologies and a commitment to scientific integrity, we empower researchers with tools designed for discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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