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TOR1AIP2 Knockout Cell Lines

Gene: TOR1AIP2

Official Full Name: torsin 1A interacting protein 2provided by HGNC

Gene Summary: One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13108 TOR1AIP2 Knockout cell line (HeLa) Human TOR1AIP2 1:3~1:6 Negative Online Inquiry
KO13109 TOR1AIP2 Knockout cell line (HCT 116) Human TOR1AIP2 1:2~1:4 Negative Online Inquiry
KO13110 TOR1AIP2 Knockout cell line (HEK293) Human TOR1AIP2 1:3~1:6 Negative Online Inquiry
KO13111 TOR1AIP2 Knockout cell line (A549) Human TOR1AIP2 1:3~1:4 Negative Online Inquiry

Background

TOR1AIP2 Gene Knockout Cell Lines are precision-engineered cellular models designed to facilitate the investigation of the TOR1AIP2 gene's function and its implications in various biological pathways. These knockout cell lines are generated using contemporary gene-editing technologies, such as CRISPR-Cas9, ensuring a high degree of specificity and efficiency in disrupting the targeted gene. By effectively eliminating TOR1AIP2 expression, these cell lines allow researchers to probe the gene's role in cellular processes such as ribosome biogenesis, stress responses, and protein synthesis, offering a clearer understanding of its contribution to diseases and developmental disorders.

The key function of these knockout cell lines lies in their ability to provide a controlled environment to study the consequences of TOR1AIP2 loss. Researchers can observe changes in cellular morphology, proliferation, and response to external stimuli, unveiling the gene's biological significance. Importantly, these cell lines serve as invaluable tools in translational research, where understanding genetic contributions to health and disease can lead to novel therapeutic strategies.

One of the unique advantages of our TOR1AIP2 Gene Knockout Cell Lines is their reproducibility and consistency across experiments, which is critical in validating findings in biological research. Compared to alternative methods, such as transient transfection or siRNA approaches, the knockout models provide stable, long-term genetic modifications that more accurately represent in vivo conditions.

For researchers and clinicians alike, the use of TOR1AIP2 Gene Knockout Cell Lines can significantly enhance experimental outcomes, streamline the drug discovery process, and support the development of innovative therapies aimed at conditions related to altered TOR1AIP2 function. With our commitment to high-quality biological products and rigorous validation processes, our company stands at the forefront of enabling impactful research and advancing our understanding of genetic influences in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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